Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection (Q39831682)

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English	Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

15 September 2017

Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection (English)

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Europe PubMed Central

PMC publication ID

15 September 2017

Helicobacter pylori

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eradication of infectious diseases

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based on heuristic

inferred from title

Antonello Covacci

7

object named as

Covacci A

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Europe PubMed Central

PMC publication ID

15 September 2017

11

object named as

Rappuoli R

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Europe PubMed Central

PMC publication ID

15 September 2017

Mariagrazia Pizza

10

object named as

Pizza M

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PMC publication ID

15 September 2017

author name string

Ghiara P

1

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Europe PubMed Central

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15 September 2017

Rossi M

2

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Europe PubMed Central

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15 September 2017

Marchetti M

3

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Europe PubMed Central

PMC publication ID

15 September 2017

Di Tommaso A

4

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Europe PubMed Central

PMC publication ID

15 September 2017

Vindigni C

5

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Europe PubMed Central

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15 September 2017

Ciampolini F

6

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Europe PubMed Central

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15 September 2017

Telford JL

8

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Europe PubMed Central

PMC publication ID

15 September 2017

De Magistris MT

9

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Europe PubMed Central

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15 September 2017

Del Giudice G

12

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15 September 2017

language of work or name

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publication date

1 December 1997

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Europe PubMed Central

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15 September 2017

Infection and Immunity

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Europe PubMed Central

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15 September 2017

65

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Europe PubMed Central

PMC publication ID

15 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

4996-5002

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Differential stimulation of interleukin-12 (IL-12) and IL-10 by live and killed Helicobacter pylori in vitro and association of IL-12 production with gamma interferon-producing T cells in the human gastric mucosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: role of VacA and CagA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection of inbred and congenic mouse strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Helicobacter pylori infection and gastric lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Recombinant antigens prepared from the urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: potential new therapies and vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Helicobacter pylori reinfection with identical organisms: transmission by the patients' spouses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Helicobacter pylori infection and the risk of gastric carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

22 September 2017

Compliance, adverse events and antibiotic resistance in Helicobacter pylori treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

25 September 2017

Current indications for Helicobacter pylori eradication therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

25 September 2017

The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

25 September 2017

A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

25 September 2017

Antimicrobial therapy for Helicobacter pylori infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

17 June 2018

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

17 June 2018

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

17 June 2018

Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

17 June 2018

Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

17 June 2018

Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

20 August 2018

Development of a mouse model of Helicobacter pylori infection that mimics human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

20 August 2018

Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175721

20 August 2018

Therapeutic immunisation against Helicobacter infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouth-to-mouth resuscitation and Helicobacter pylori infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic immunization against Helicobacter mustelae in naturally infected ferrets

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial resistance and Helicobacter pylori

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunisation against gastric helicobacter infection in a mouse/Helicobacter felis model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9393788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.65.12.4996-5002.1997

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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