Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. (Q39829317)

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1 February 2020

title

Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease (English)

1 reference

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metabolic dysfunction–associated steatotic liver disease

1 February 2020

main subject

1 reference

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1 February 2020

Javier Conde-Vancells

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1 February 2020

Wing-Kin Syn

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1 February 2020

Youngmi Jung

1 reference

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1 February 2020

Manal Abdelmalek

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1 February 2020

Cynthia D Guy

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1 February 2020

Liu Yang

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1 February 2020

Jiangbo Wang

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1 February 2020

Rafal P Witek

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1 February 2020

Caitlin M Fearing

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1 February 2020

Thiago A Pereira

1 reference

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1 February 2020

Vanessa Teaberry

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1 February 2020

Steve S Choi

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1 February 2020

Gamze F Karaca

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1 February 2020

Anna Mae Diehl

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1 February 2020

language of work or name

English

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publication date

3 July 2009

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1 February 2020

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1 February 2020

volume

137

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issue

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1 February 2020

page(s)

1478-1488.e8

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Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

1 February 2020

cites work

1 reference

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Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways

22 September 2017

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Functional Wnt signaling is increased in idiopathic pulmonary fibrosis

22 September 2017

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Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans

22 September 2017

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Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.

22 September 2017

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Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye.

22 September 2017

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Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway

22 September 2017

1 reference

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Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice

22 September 2017

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Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins

22 September 2017

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Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro

22 September 2017

1 reference

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Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats

22 September 2017

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Hedgehog signaling maintains resident hepatic progenitors throughout life

22 September 2017

1 reference

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Role for hedgehog signaling in hepatic stellate cell activation and viability

22 September 2017

1 reference

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Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis

22 September 2017

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22 September 2017

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Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells

22 September 2017

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Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein.

22 September 2017

1 reference

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Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease

22 September 2017

1 reference

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Epithelial-mesenchymal transitions in development and pathologies

22 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

22 September 2017

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Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease

22 September 2017

1 reference

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

22 September 2017

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Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions

22 September 2017

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Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease

22 September 2017

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Early role of Fsp1 in epithelial-mesenchymal transformation

22 September 2017

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An overview of epithelio-mesenchymal transformation

22 September 2017

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Identification and characterization of a fibroblast marker: FSP1

22 September 2017

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Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells

22 September 2017

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Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

25 September 2017

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The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

17 June 2018

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Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.

20 August 2018

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Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.

20 August 2018

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The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies

20 August 2018

1 reference

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BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

20 August 2018

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Medulloblastoma growth inhibition by hedgehog pathway blockade

20 August 2018

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A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver

20 August 2018

1 reference

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Ductular reaction and its diagnostic significance.

20 August 2018

1 reference

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Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney

20 August 2018

1 reference

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Nonalcoholic fatty liver disease

2 December 2018

1 reference

12 December 2020

The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes

1 reference

12 December 2020

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

1 reference

12 December 2020

Differentiation of oval cells into duct-like cells in preneoplastic liver of rats placed on a choline-deficient diet supplemented with ethionine

1 reference

12 December 2020

Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation

1 reference

12 December 2020

The oval-shaped cell as a candidate for a liver stem cell in embryonic, neonatal and precancerous liver: identification based on morphology and immunohistochemical staining for albumin and pyruvate kinase isoenzyme expression

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12 December 2020

Primary culture of cholangiocytes from normal mouse liver

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12 December 2020

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

1 reference

12 December 2020

Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation

1 reference

12 December 2020

10.1053/J.GASTRO.2009.06.051

Identifiers

DOI

1 reference

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1 February 2020

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1 February 2020

PubMed publication ID

19577569

1 reference

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