IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations. (Q39767662)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755637%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

title

IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations (English)

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18 October 2019

0 references

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chronic lymphocytic leukemia

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18 October 2019

Ivanovski M

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18 October 2019

Batista FD

series ordinal

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18 October 2019

Pozzato G

series ordinal

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18 October 2019

Burrone OR

series ordinal

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18 October 2019

language of work or name

English

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publication date

1 July 1996

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Journal of Clinical Investigation

18 October 2019

published in

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18 October 2019

volume

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18 October 2019

issue

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18 October 2019

page(s)

290-298

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Molecular analysis of VH and VL regions expressed in IgG-bearing chronic lymphocytic leukemia (CLL): further evidence that CLL is a heterogeneous group of tumors

18 October 2019

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Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

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Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells

22 September 2017

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22 September 2017

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Molecular Basis of Heavy-Chain Class Switching and Switch Region Deletion in an Abelson Virus-Transformed Cell Line

22 September 2017

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Idiotypic Specificity of Surface Immunoglobulin and the Maturation of Leukemic Bone-marrow-derived Lymphocytes

22 September 2017

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Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

22 September 2017

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

22 September 2017

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Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation

22 September 2017

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Chronic lymphocytic leukemia: new insights into biology and therapy

22 September 2017

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B-cell chronic lymphocytic leukemia: present status and future directions. French Cooperative Group on CLL.

22 September 2017

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The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

22 September 2017

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Extensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia

22 September 2017

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Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes

22 September 2017

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Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases.

22 September 2017

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Intraclonal generation of antibody mutants in germinal centres

25 September 2017

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Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse

25 September 2017

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Molecular analysis of IgE H-chain transcripts expressed in vivo by peripheral blood lymphocytes from normal and atopic individuals

25 September 2017

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Phenotypic markers and BCL-1 gene rearrangements in B-cell chronic lymphocytic leukemia: a Cancer and Leukemia Group B study.

15 June 2018

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The incidence, clonal origin and secretory nature of serum paraproteins in chronic lymphocytic leukaemia

15 June 2018

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IgE synthesis by chronic lymphocytic leukemia cells

15 June 2018

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Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with B-cell chronic lymphocytic leukemia

15 June 2018

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Intraclonal diversity in the VH genes expressed by CD5- chronic lymphocytic leukemia-producing pathologic IgM rheumatoid factor

15 June 2018

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Transcription of unrearranged Ig H chain genes in human B cell malignancies. Biased expression of genes encoded within the first duplication unit of the Ig H chain locus.

15 June 2018

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Variable region gene analysis of an isotype-switched (IgA) variant of chronic lymphocytic leukemia

15 June 2018

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15 June 2018

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20 August 2018

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20 August 2018

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20 August 2018

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12 December 2020

Mitogen-induced switching of immunoglobulin heavy-chain class secretion in chronic B-lymphocytic leukaemia and immunocytoma cell populations

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12 December 2020

Circulating monoclonal IgM proteins in B cell chronic lymphocytic leukemia: their identification, characterization and relationship to membrane IgM

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12 December 2020

High incidence of monoclonal proteins in the serum and urine of chronic lymphocytic leukemia patients

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12 December 2020

Clonal B-cell expansions in peripheral blood of HCV-infected patients

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12 December 2020

Restricted immunoglobulin VH region repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia

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12 December 2020

Monoclonal Bence Jones proteinuria in chronic lymphocytic leukaemia

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12 December 2020

Autoimmune hemolytic anemia

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12 December 2020

High incidence of serum monoclonal Igs detected by a sensitive immunoblotting technique in B-cell chronic lymphocytic leukemia

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12 December 2020

Identifiers

DOI

10.1172/JCI118792

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755637%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755637%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

PubMed publication ID

8755637

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8755637%20AND%20SRC:MED&resulttype=core&format=json