Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility (Q39756940)

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English	Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

1 reference

based on heuristic

inferred from title

object named as

Neil A Mabbott

1

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author name string

Janice Young

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Irene McConnell

3

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Europe PubMed Central

PMC publication ID

14 September 2017

Moira E Bruce

4

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Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

1 June 2003

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Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Virology

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Europe PubMed Central

PMC publication ID

14 September 2017

77

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Europe PubMed Central

PMC publication ID

14 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

6845-6854

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Accumulation of prion protein in tonsil and appendix: review of tissue samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Drug and gene targeting to the brain with molecular Trojan horses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Follicular dendritic cells and dissemination of Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

The role of complement in the acquired immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Prion protein expression in different species: analysis with a panel of new mAbs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Role of complement in the induction of immunological responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

22 September 2017

Establishment of a follicular lymphoma cell line (FLK-1) dependent on follicular dendritic cell-like cell line HK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

25 September 2017

Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Follicular dendritic cells (FDC) in retroviral infection: host/pathogen perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

To 'B' or not to 'B' a germinal center?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Genetical control of the concentration of ME7 scrapie agent in the brain of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

Pathogenesis of scrapie in mice after intragastric infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

15 June 2018

PrP(CWD) lymphoid cell targets in early and advanced chronic wasting disease of mule deer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Complement facilitates early prion pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Pathogenesis of the oral route of infection of mice with scrapie and bovine spongiform encephalopathy agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Scrapie-associated prion protein in the gastrointestinal tract of sheep with natural scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Cytokine regulation of secondary lymphoid organ development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Identification of a protein that purifies with the scrapie prion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

Effect of mouse peritoneal macrophages on scrapie infectivity during extended in vitro incubation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

20 August 2018

PrP expression in B lymphocytes is not required for prion neuroinvasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156207

2 December 2018

Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular prion protein is expressed in the human enteric nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and accumulation of PrP in gut-associated and peripheral lymphoid tissue of scrapie-affected Suffolk sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turning off follicular dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12768004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.77.12.6845-6854.2003

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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