Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms (Q39738340)

14 September 2017

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms (English)

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14 September 2017

G Matthew Longo

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14 September 2017

Wanfen Xiong

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14 September 2017

Timothy C Greiner

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14 September 2017

Yong Zhao

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14 September 2017

Nicola Fiotti

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14 September 2017

B Timothy Baxter

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14 September 2017

language of work or name

English

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publication date

1 September 2002

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Journal of Clinical Investigation

14 September 2017

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14 September 2017

110

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14 September 2017

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14 September 2017

625-632

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Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

A modification of Movat's pentachrome stain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Aneurysm of the rabbit common carotid artery induced by periarterial application of calcium chloride in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Cellular components and features of immune response in abdominal aortic aneurysms.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Role of serine proteases in aneurysm development.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Risk factors for abdominal aortic aneurysms in older adults enrolled in The Cardiovascular Health Study

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Human vascular smooth muscle cell-monocyte interactions and metalloproteinase secretion in culture.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Role of reactive oxygen species in IL-1 beta-stimulated sustained ERK activation and MMP-9 induction

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151106

Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms

20 August 2018

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12 December 2020

Immunophenotypic analysis of the aortic aneurysm wall suggests that vascular dendritic cells are involved in immune responses

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12 December 2020

"Variable induction of experimental abdominal aortic aneurysms with different preparations of porcine pancreatic elastase"

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12 December 2020

Effects of noninhibitory alpha-1-antitrypsin on primary human monocyte activation in vitro

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12 December 2020

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

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12 December 2020

Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice

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12 December 2020

Elastase-induced experimental aneurysms in rats

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12 December 2020

Expression of 92 kDa phagocyte gelatinase by inflammatory and connective tissue cells

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12 December 2020

Abdominal aortic aneurysm

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12 December 2020

Failure of elastin or collagen as possible critical connective tissue alterations underlying aneurysmal dilatation

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12 December 2020

Cytokines that activate proteolysis are increased in abdominal aortic aneurysms

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12 December 2020

Matrix metalloproteinases in abdominal aortic aneurysm: characterization, purification, and their possible sources

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12 December 2020

Interleukin-1 beta induces differential gene expression in aortic smooth muscle cells

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12 December 2020

Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm

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12 December 2020

Anti-CD 18 monoclonal antibody slows experimental aortic aneurysm expansion

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12 December 2020

Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase

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12 December 2020

Identifiers

DOI

10.1172/JCI0215334

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14 September 2017

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14 September 2017

PubMed publication ID

12208863

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