Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin (Q39707870)

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English	Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin (English)

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Europe PubMed Central

PubMed publication ID

14 September 2017

apoptotic process

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phosphorylation

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multiple drug resistance

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author name string

Li Wang

1

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Europe PubMed Central

PubMed publication ID

14 September 2017

Fang Yin

2

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14 September 2017

Yulei Du

3

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14 September 2017

Bei Chen

4

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14 September 2017

Shuhui Liang

5

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14 September 2017

Yongguo Zhang

6

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14 September 2017

Wenqi Du

7

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Europe PubMed Central

PubMed publication ID

14 September 2017

Kaichun Wu

8

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14 September 2017

Jie Ding

9

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14 September 2017

Daiming Fan

10

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14 September 2017

publication date

4 May 2010

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14 September 2017

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Europe PubMed Central

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14 September 2017

31

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14 September 2017

3

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14 September 2017

225-232

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14 September 2017

Polo-like kinase-1 is a target of the DNA damage checkpoint

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Aberrant MAD2 expression in soft-tissue sarcoma

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Biological response to phorbol ester determined by alternative G1 pathways

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells.

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Activation of CDC 25 phosphatase and CDC 2 kinase involved in GL331-induced apoptosis

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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DNA Damage during the Spindle-Assembly Checkpoint Degrades CDC25A, Inhibits Cyclin–CDC2 Complexes, and Reverses Cells to Interphase

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Cell Division Gatekeepers Identified

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Overexpression of spindlin1 induces metaphase arrest and chromosomal instability

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes, hsMAD2 and p55CDC, in human lung cancers

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Mitosis: don't get mad, get even

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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The spindle checkpoint: structural insights into dynamic signalling

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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No somatic mutations detected in the Mad2 gene in 658 human tumors

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Mad2beta, an alternative variant of Mad2 reducing mitotic arrest and apoptosis induced by adriamycin in gastric cancer cells.

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Expression of seven main Rho family members in gastric carcinoma

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells.

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Control of mitotic transitions by the anaphase-promoting complex

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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[Multidrug resistant effect of alternative splicing form of MAD2 gene-MAD2beta on human gastric cancer cell].

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

based on heuristic

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Identification of a human mitotic checkpoint gene: hsMAD2

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Role of cell cycle in mediating sensitivity to radiotherapy

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Differentially expressed gene profiles between multidrug resistant gastric adenocarcinoma cells and their parental cells

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Development of cell cycle active drugs for the treatment of gastrointestinal cancers: a new approach to cancer therapy

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Depression of MAD2 inhibits apoptosis of gastric cancer cells by upregulating Bcl-2 and interfering mitochondrion pathway

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

based on heuristic

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Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

based on heuristic

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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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MAD2 interacts with DNA repair proteins and negatively regulates DNA damage repair

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Cisplatin stops tubulin assembly into microtubules. A new insight into the mechanism of antitumor activity of platinum complexes.

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https://pubmed.ncbi.nlm.nih.gov/20440596

12 December 2020

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Identifiers

10.1007/S13277-010-0036-6

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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