Fine structure and activity of discrete RAG-HMG complexes on V(D)J recombination signals (Q39677703)

13 September 2017

Fine structure and activity of discrete RAG-HMG complexes on V(D)J recombination signals (English)

1 reference

13 September 2017

Patrick C Swanson

1 reference

13 September 2017

language of work or name

English

0 references

publication date

1 March 2002

1 reference

Molecular and Cellular Biology

13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

1340-1351

1 reference

describes a project that uses

13 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC134695/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The RAG proteins in V(D)J recombination: more than just a nuclease

1 reference

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HMG1 and 2, and related 'architectural' DNA-binding proteins

14 September 2017

1 reference

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The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

14 September 2017

1 reference

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

14 September 2017

1 reference

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Mechanism for specificity by HMG-1 in enhanceosome assembly

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Flexing DNA: HMG-box proteins and their partners.

14 September 2017

1 reference

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V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

RAG-1 and RAG-2-Dependent Assembly of Functional Complexes with V(D)J Recombination Substrates in Solution

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Stimulation of V(D)J cleavage by high mobility group proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Characterization of broken DNA molecules associated with V(D)J recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Specific photocrosslinking of DNA-protein complexes: identification of contacts between integration host factor and its target DNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The V(D)J recombination activating gene, RAG-1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134695

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11839801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11839801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.5.1340-1351.2002

1 reference

13 September 2017

1 reference

13 September 2017

PubMed publication ID

11839801

1 reference