Pathogenic lysosomal depletion in Parkinson's disease (Q39655523)

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scientific article published on September 2010

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English	Pathogenic lysosomal depletion in Parkinson's disease	scientific article published on September 2010

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

20844148

retrieved

13 September 2017

title

Pathogenic lysosomal depletion in Parkinson's disease (English)

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stated in

Europe PubMed Central

PubMed publication ID

20844148

retrieved

13 September 2017

main subject

Parkinson's disease

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inferred from title

author

Miquel Vila

series ordinal

7

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stated in

Europe PubMed Central

PMC publication ID

6633458

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

Benjamin Dehay

series ordinal

1

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Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

Natalia Rodríguez-Muela

series ordinal

3

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Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

Ariadna Recasens

series ordinal

5

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Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

Patricia Boya

series ordinal

6

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stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

author name string

Jordi Bové

series ordinal

2

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stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

Celine Perier

series ordinal

4

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stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

language of work or name

English

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publication date

1 September 2010

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20844148

retrieved

13 September 2017

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

volume

30

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stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

issue

37

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stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

page(s)

12535-12544

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Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

cites work

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

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inferred from PubMed ID database lookup

The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

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Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

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Targeting programmed cell death in neurodegenerative diseases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: mechanisms and models

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sucrose-induced vacuolation results in increased expression of cholesterol biosynthesis and lysosomal genes

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lewy bodies

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocerebrosidase mutations are an important risk factor for Lewy body disorders

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain is required for macroautophagy in mammalian cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How to interpret LC3 immunoblotting

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomes: fusion and function

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROS, mitochondria and the regulation of autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructure of Lewy bodies in the stellate ganglion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy: process and function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy in the Pathogenesis of Disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial alterations in Parkinson's disease: new clues

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal membrane permeabilization in cell death

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A gene network regulating lysosomal biogenesis and function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal Biogenesis in Lysosomal Storage Disorders

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20844148

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.1920-10.2010

1 reference

stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

PMC publication ID

6633458

1 reference

stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

PubMed publication ID

20844148

1 reference

stated in

Europe PubMed Central

PMC publication ID

6633458

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6633458&resulttype=core&format=json

retrieved

15 May 2020

ResearchGate publication ID

46281527

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