The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane (Q39612709)

19 May 2018

title

The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane (English)

1 reference

19 May 2018

0 references

1 reference

Wenyan Xu

1 reference

19 May 2018

Miaomiao Jin

1 reference

19 May 2018

Ruikun Hu

1 reference

19 May 2018

Hong Wang

1 reference

19 May 2018

Fan Zhang

1 reference

19 May 2018

Shiaulou Yuan

1 reference

19 May 2018

Ying Cao

1 reference

19 May 2018

publication date

8 July 2016

1 reference

19 May 2018

Journal of the American Society of Nephrology

published in

1 reference

19 May 2018

volume

1 reference

19 May 2018

issue

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19 May 2018

page(s)

118-129

1 reference

19 May 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5198270/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis

1 reference

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Ciliary Phosphoinositide Regulates Ciliary Protein Trafficking in Drosophila.

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Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling

17 June 2018

1 reference

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Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.

17 June 2018

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The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

17 June 2018

1 reference

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INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability

17 June 2018

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PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

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ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

17 June 2018

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Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish

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Soluble levels of cytosolic tubulin regulate ciliary length control

17 June 2018

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Intraflagellar transport proteins are essential for cilia formation and for planar cell polarity

17 June 2018

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The primary cilium: a signalling centre during vertebrate development

17 June 2018

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Functional genomic screen for modulators of ciliogenesis and cilium length

17 June 2018

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17 June 2018

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Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides

17 June 2018

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Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies

17 June 2018

1 reference

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INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish

17 June 2018

1 reference

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Properties of an ezrin mutant defective in F-actin binding

17 June 2018

1 reference

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Polycystic kidney disease

17 June 2018

1 reference

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Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

17 June 2018

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17 June 2018

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17 June 2018

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Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells

17 June 2018

1 reference

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Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains

17 June 2018

1 reference

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RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1

17 June 2018

1 reference

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PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

17 June 2018

1 reference

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Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

17 June 2018

1 reference

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Phosphoinositides in cell regulation and membrane dynamics

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

17 June 2018

1 reference

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Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology.

17 June 2018

1 reference

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A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Both foxj1a and foxj1b are implicated in left-right asymmetric development in zebrafish embryos

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Identification of regulators of germ layer morphogenesis using proteomics in zebrafish

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Spatial and temporal expression of the zebrafish genome by large-scale in situ hybridization screening.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

F(ab) secondary antibodies: a general method for double immunolabeling with primary antisera from the same species. Efficiency control by chemiluminescence

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5198270

Identification of a phosphatidylinositol-4,5-bisphosphate-binding domain in the N-terminal region of ezrin

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27401686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1681/ASN.2015080906

1 reference

19 May 2018

PMC publication ID

5198270

1 reference

19 May 2018

PubMed publication ID

27401686

1 reference

19 May 2018