The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model (Q39604863)

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scientific article published on January 21, 2011

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English	The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model	scientific article published on January 21, 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 September 2017

The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

author name string

Tamar Tadmor

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Yu Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Hyun-Mi Cho

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Eckhard R. Podack

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

Joseph D. Rosenblatt

5

0000-0003-0798-0403

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

language of work or name

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21253724

22 November 2024

publication date

21 January 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11028831

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

https://europepmc.org/articles/PMC11028831

online access status

content deliverer

Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

https://europepmc.org/articles/PMC11028831?pdf=render

Portable Document Format

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Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

https://doi.org/10.1007/s00262-011-0972-z

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21253724

22 November 2024

http://link.springer.com/content/pdf/10.1007/s00262-011-0972-z.pdf

Portable Document Format

1 reference

10.1007/S00262-011-0972-Z

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22 November 2024

http://link.springer.com/article/10.1007/s00262-011-0972-z/fulltext.html

1 reference

10.1007/S00262-011-0972-Z

https://api.crossref.org/works/10.1007/S00262-011-0972-Z

22 November 2024

http://link.springer.com/content/pdf/10.1007/s00262-011-0972-z

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1 reference

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PubMed publication ID

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609-619

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B cells and professional APCs recruit regulatory T cells via CCL4

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Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells

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B cells inhibit induction of T cell-dependent tumor immunity.

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Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells

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Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells.

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Inhibitory effects of B cells on antitumor immunity.

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Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance

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Regulatory T cells in cancer

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Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse

7

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Cutting edge: primary B lymphocytes preferentially expand allogeneic FoxP3+ CD4 T cells

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The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance

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Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

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Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells

13

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BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice

17

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Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent

18

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A case for regulatory B cells

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A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses

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Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

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B-cell depletion using an anti-CD20 antibody augments antitumor immune responses and immunotherapy in nonhematopoetic murine tumor models

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Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

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Identifiers

10.1007/S00262-011-0972-Z

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PMC publication ID

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21253724

22 November 2024

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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