Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase (Q39599563)

13 September 2017

Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase (English)

1 reference

13 September 2017

Haitao Li

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13 September 2017

Hongmei Cui

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13 September 2017

Tapan Kumar Kundu

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13 September 2017

Wael Alzawahra

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13 September 2017

Jay L Zweier

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13 September 2017

language of work or name

English

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publication date

18 April 2008

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Journal of Biological Chemistry

13 September 2017

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13 September 2017

283

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13 September 2017

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13 September 2017

17855-17863

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Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Characterization of the mechanism of cytochrome P450 reductase-cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide: mechanism(s) and physiologic versus pathophysiologic relevance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Xanthine oxidase and aldehyde oxidase: a simple procedure for the simultaneous purification from rat liver

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Non-enzymatic nitric oxide synthesis in biological systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Purification, cDNA cloning, and tissue distribution of bovine liver aldehyde oxidase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Measurement of tissue purine, pyrimidine, and other nucleotides by radial compression high-performance liquid chromatography

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Molybdenum hydroxylases: biological distribution and substrate-inhibitor specificity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Effect of nitrite on rabbit liver mixed-function oxidase activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Guinea pig liver aldehyde oxidase as a sulfoxide reductase: its purification and characterization.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Tissue distribution of the molybdenum hydroxylases, aldehyde oxidase and xanthine oxidase, in male and female guinea pigs

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

The activity of xanthine oxidase in heart of pigs, guinea pigs, rabbits, rats, and humans.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Estimation of nitric oxide concentration in blood for different rates of generation. Evidence that intravascular nitric oxide levels are too low to exert physiological effects

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Immuno-spin trapping of hemoglobin and myoglobin radicals derived from nitrite-mediated oxidation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Hemoglobin as a nitrite reductase regulating red cell-dependent hypoxic vasodilation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Characterization of perceived hyperoxia in isolated primary cardiac fibroblasts and in the reoxygenated heart.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Oxygen sensing by primary cardiac fibroblasts: a key role of p21(Waf1/Cip1/Sdi1).

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Mitochondria recycle nitrite back to the bioregulator nitric monoxide

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Intragastric nitric oxide production in humans: measurements in expelled air.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Nature of the free-radical states in microsomes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440597

Generation of Nitric Oxide by a Nitrite Reductase Activity of Xanthine Oxidase: A Potential Pathway for Nitric Oxide Formation in the Absence of Nitric Oxide Synthase Activity

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M801785200

Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase

21 January 2018

1 reference

12 December 2020

Active nitric oxide produced in the red cell under hypoxic conditions by deoxyhemoglobin-mediated nitrite reduction

1 reference

12 December 2020

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

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12 December 2020

Ion implicated in blood pact

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12 December 2020

Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites

1 reference

12 December 2020

Sodium N-methyl-D-glucamine dithiocarbamate and cadmium intoxication

1 reference

12 December 2020

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1 reference

12 December 2020

1 reference

12 December 2020

Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy

1 reference

12 December 2020

Effect of nitric oxide and cell redox status on the regulation of endothelial cell xanthine dehydrogenase

1 reference

12 December 2020

Substrate Control of Free Radical Generation from Xanthine Oxidase in the Postischemic Heart

1 reference

12 December 2020

Enzyme-independent formation of nitric oxide in biological tissues

1 reference

12 December 2020

Organ distribution and molecular forms of human xanthine dehydrogenase/xanthine oxidase protein

1 reference

12 December 2020

Immunohistochemical localization of aldehyde and xanthine oxidase in rat tissues using polyclonal antibodies

1 reference

12 December 2020

Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide

1 reference

12 December 2020

Decreased Nitric-oxide Synthase Activity Causes Impaired Endothelium-dependent Relaxation in the Postischemic Heart

1 reference

12 December 2020

Development of chemiluminescence-based methods for specific quantitation of nitrosylated thiols

1 reference

12 December 2020

Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions

1 reference

12 December 2020

Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems

1 reference

12 December 2020

Nitrite reductase activity is a novel function of mammalian mitochondria

1 reference

12 December 2020

The emerging biology of the nitrite anion

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M801785200

1 reference

13 September 2017

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13 September 2017

PubMed publication ID

18424432

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