Mapping of signaling networks through synthetic genetic interaction analysis by RNAi (Q39580460)

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scientific article published on 6 March 2011

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English	Mapping of signaling networks through synthetic genetic interaction analysis by RNAi	scientific article published on 6 March 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

21378980

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13 September 2017

title

Mapping of signaling networks through synthetic genetic interaction analysis by RNAi (English)

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PubMed publication ID

21378980

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13 September 2017

author

Wolfgang Huber

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5

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PubMed publication ID

21378980

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13 September 2017

Bernd Fischer

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Bernd Fischer

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3

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Thomas Horn

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1

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PubMed publication ID

21378980

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13 September 2017

Thomas Sandmann

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2

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Europe PubMed Central

PubMed publication ID

21378980

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13 September 2017

Elin Axelsson

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4

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Europe PubMed Central

PubMed publication ID

21378980

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Michael Boutros

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6

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Europe PubMed Central

PubMed publication ID

21378980

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13 September 2017

publication date

6 March 2011

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PubMed publication ID

21378980

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13 September 2017

published in

Nature Methods

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PubMed publication ID

21378980

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13 September 2017

volume

8

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21378980

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issue

4

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21378980

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page(s)

341-346

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21378980

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Phosphorylation networks regulating JNK activity in diverse genetic backgrounds

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The PDGF/VEGF receptor controls blood cell survival in Drosophila

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A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling.

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RNAi screening in cultured Drosophila cells.

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Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity

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A global analysis of genetic interactions in Caenorhabditis elegans

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Genotype to phenotype: a complex problem

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The genetic landscape of a cell

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CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.

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Global mapping of the yeast genetic interaction network

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Statistical significance for genomewide studies

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Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling

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Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

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Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

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Genome-wide RNAi analysis of growth and viability in Drosophila cells

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A note on the background to, and refereeing of, R. A. Fisher's 1918 paper 'On the correlation between relatives on the supposition of Mendelian inheritance'.

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Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

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Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis

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Finding the missing heritability of complex diseases

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Design and evaluation of genome-wide libraries for RNA interference screens

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Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

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Defining genetic interaction

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p145, a major Grb2-binding protein in brain, is co-localized with dynamin in nerve terminals where it undergoes activity-dependent dephosphorylation.

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Optimal stepwise experimental design for pairwise functional interaction studies

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QuantPrime--a flexible tool for reliable high-throughput primer design for quantitative PCR.

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based on heuristic

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DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions

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Synergistic drug combinations tend to improve therapeutically relevant selectivity

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A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

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Automated identification of pathways from quantitative genetic interaction data

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Identifiers

DOI

10.1038/NMETH.1581

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Europe PubMed Central

PubMed publication ID

21378980

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13 September 2017

Dimensions Publication ID

1039061795

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Fatcat ID

release_p62gaxymdrd2jkiz2ydhjslbqi

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PubMed publication ID

21378980

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21378980

retrieved

13 September 2017

ResearchGate publication ID

50290125

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