Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1 (Q39536018)

12 September 2017

title

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1 (English)

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2011.07318.X

3 December 2024

main subject

protein ubiquitination

1 reference

Liliane Glauser

1 reference

12 September 2017

Klodjan Stafa

1 reference

12 September 2017

Darren J. Moore

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21615408

3 December 2024

Sarah Sonnay

1 reference

12 September 2017

language of work or name

English

0 references

publication date

6 June 2011

1 reference

full work available at URL

12 September 2017

1 reference

inferred from page(s)

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1471-4159.2011.07318.x

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21615408

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1471-4159.2011.07318.x

3 December 2024

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2011.07318.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1471-4159.2011.07318.x

3 December 2024

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2011.07318.X

Journal of Neurochemistry

3 December 2024

published in

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12 September 2017

volume

118

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12 September 2017

1 reference

12 September 2017

page(s)

636-645

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Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mendelian forms of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The emerging complexity of protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Parkin: a multifaceted ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Parkin mediates the degradation-independent ubiquitination of Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Real-time monitoring of ubiquitination in living cells by BRET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07318.X

21 January 2018

Identifiers

1 reference

12 September 2017

1 reference