Computational design of novel protein binders and experimental affinity maturation (Q39464749)

12 September 2017

title

Computational design of novel protein binders and experimental affinity maturation (English)

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12 September 2017

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computational biology

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Sarel J Fleishman

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David Baker

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Timothy A Whitehead

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12 September 2017

language of work or name

English

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publication date

1 January 2013

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12 September 2017

published in

Methods in Enzymology

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12 September 2017

volume

523

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12 September 2017

page(s)

1-19

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Native protein sequences are close to optimal for their structures

12 September 2017

cites work

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1073/PNAS.97.19.10383

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Role of the biomolecular energy gap in protein design, structure, and evolution

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.CELL.2012.03.016

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Community-wide assessment of protein-interface modeling suggests improvements to design methodology

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.JMB.2011.09.031

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Restricted sidechain plasticity in the structures of native proteins and complexes

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1002/PRO.604

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A phage display system for studying the sequence determinants of protein folding

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1002/PRO.5560040609

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A De Novo Protein Binding Pair By Computational Design and Directed Evolution

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.MOLCEL.2011.03.010

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1126/SCIENCE.1202617

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1038/NBT.2214

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

High-resolution mapping of protein sequence-function relationships

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1038/NMETH.1492

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Hotspot-centric de novo design of protein binders

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.JMB.2011.09.001

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite

2 references

9 October 2024

https://opencitations.net/index/api/v1/citations/10.1371/JOURNAL.PONE.0020161

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

The atomic structure of protein-protein recognition sites

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Anatomy of hot spots in protein interfaces

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Broadly neutralizing antibodies against influenza virus and prospects for universal therapies

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

PatchDock and SymmDock: servers for rigid and symmetric docking

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Computational mapping of anchoring spots on protein surfaces

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Macromolecular modeling with rosetta

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Isolating and engineering human antibodies using yeast surface display

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

AutoMatch: target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Antibody recognition of a highly conserved influenza virus epitope

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Deep mutational scanning: assessing protein function on a massive scale

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Protein production by auto-induction in high density shaking cultures

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Prediction of protein-protein interface sequence diversity using flexible backbone computational protein design

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Nonnatural protein-protein interaction-pair design by key residues grafting

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Modelling protein docking using shape complementarity, electrostatics and biochemical information

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A highly conserved neutralizing epitope on group 2 influenza A viruses

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Molecular surface recognition: determination of geometric fit between proteins and their ligands by correlation techniques

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Computational design of a PAK1 binding protein

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A hot spot of binding energy in a hormone-receptor interface

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Engineering antibody affinity by yeast surface display.

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

An improved yeast transformation method for the generation of very large human antibody libraries

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Assembly of Cell Regulatory Systems Through Protein Interaction Domains

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

A de novo designed protein protein interface

1 reference

9 October 2024

https://opencitations.net/index/api/v1/references/10.1016/B978-0-12-394292-0.00001-1

Identifiers

DOI

10.1016/B978-0-12-394292-0.00001-1

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12 September 2017

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