Mitochondrial Dynamics in Regulating the Unique Phenotypes of Cancer and Stem Cells (Q39397584)

10 July 2018

review article

1 reference

title

Mitochondrial Dynamics in Regulating the Unique Phenotypes of Cancer and Stem Cells (English)

1 reference

10 July 2018

author name string

Hsiuchen Chen

series ordinal

1 reference

10 July 2018

David C Chan

series ordinal

1 reference

10 July 2018

publication date

22 June 2017

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10 July 2018

published in

Cell Metabolism

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10 July 2018

volume

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10 July 2018

issue

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10 July 2018

page(s)

39-48

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10 July 2018

MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling

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Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

15 July 2018

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Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma

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15 July 2018

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15 July 2018

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Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

15 July 2018

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Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration

15 July 2018

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Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

15 July 2018

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15 July 2018

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Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.

15 July 2018

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15 July 2018

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Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth

15 July 2018

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Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

15 July 2018

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Mitochondrial DNA: impacting central and peripheral nervous systems

15 July 2018

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Determinants and functions of mitochondrial behavior

15 July 2018

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Tackling the cancer stem cells - what challenges do they pose?

15 July 2018

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Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells.

15 July 2018

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15 July 2018

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UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation.

15 July 2018

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Mutations in Fis1 disrupt orderly disposal of defective mitochondria

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

15 July 2018

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Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.

15 July 2018

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Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

15 July 2018

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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

15 July 2018

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Mitochondrial dynamics regulates migration and invasion of breast cancer cells

15 July 2018

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Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal

15 July 2018

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Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress

15 July 2018

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Fusion and fission: interlinked processes critical for mitochondrial health

15 July 2018

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15 July 2018

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DRP1-dependent mitochondrial fission initiates follicle cell differentiation during Drosophila oogenesis

15 July 2018

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15 July 2018

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15 July 2018

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Dynamin, a membrane-remodelling GTPase

15 July 2018

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UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

15 July 2018

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15 July 2018

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ER Tubules Mark Sites of Mitochondrial Division

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

15 July 2018

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15 July 2018

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15 July 2018

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Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

15 July 2018

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A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

15 July 2018

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Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

15 July 2018

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Naive and primed pluripotent states

15 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

15 July 2018

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

15 July 2018

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Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

15 July 2018

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Mitochondrial dynamics and apoptosis

15 July 2018

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The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

15 July 2018

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

15 July 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

15 July 2018

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OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

15 July 2018

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A lethal defect of mitochondrial and peroxisomal fission

15 July 2018

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Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

15 July 2018

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The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells

15 July 2018

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Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

15 July 2018

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

15 July 2018

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

15 July 2018

1 reference

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Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress

15 July 2018

1 reference

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Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell

15 July 2018

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Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape

15 July 2018

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15 July 2018

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The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species

15 July 2018

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NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion

21 August 2018

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Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

21 August 2018

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A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy.

21 August 2018

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Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and function

21 August 2018

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Lethal Disorder of Mitochondrial Fission Caused by Mutations in DNM1L.

21 August 2018

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Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency

21 August 2018

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Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes

21 August 2018

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The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

21 August 2018

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 August 2018

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Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines.

21 August 2018

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Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors.

21 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5539982

Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling

21 August 2018

1 reference

12 December 2020

Metabolic switches linked to pluripotency and embryonic stem cell differentiation

1 reference

12 December 2020

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

1 reference

12 December 2020

Orientation of the Mitochondria during Mitosis

1 reference

12 December 2020

10.1016/J.CMET.2017.05.016

Identifiers

DOI

1 reference

10 July 2018

PMC publication ID

5539982

1 reference

10 July 2018

PubMed publication ID

28648983

1 reference

10 July 2018