The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients (Q39218930)

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English	The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients	scientific article

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scholarly article

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10 September 2017

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients (English)

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10 September 2017

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white blood cell

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Noelia Diaz-Morales

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4 June 2020

Susana Rovira-Llopis

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4 June 2020

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4 June 2020

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4 June 2020

Michael P. Murphy

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4 June 2020

Víctor M Víctor

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4 June 2020

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Irene Escribano-Lopez

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4 June 2020

Arantxa Martinez de Marañon

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4 June 2020

Samuel Orden

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4 June 2020

Angeles Alvarez

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4 June 2020

Antonio Hernandez-Mijares

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4 June 2020

publication date

27 October 2016

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10 September 2017

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4 June 2020

10

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4 June 2020

200-205

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4 June 2020

A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats

1 reference

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10 September 2017

The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Pancreatic β-cell dysfunction in polycystic ovary syndrome: role of hyperglycemia-induced nuclear factor-κB activation and systemic inflammation.

1 reference

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10 September 2017

Central inhibition of IKKβ/NF-κB signaling attenuates high-fat diet-induced obesity and glucose intolerance.

1 reference

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10 September 2017

Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.

1 reference

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10 September 2017

Antioxidants successfully reduce ROS production in propionic acidemia fibroblasts

1 reference

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10 September 2017

Nuclear NF-κB p65 in peripheral blood mononuclear cells correlates with urinary MCP-1, RANTES and the severity of type 2 diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Reactive oxygen species in inflammation and tissue injury

1 reference

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10 September 2017

Human leukocyte/endothelial cell interactions and mitochondrial dysfunction in type 2 diabetic patients and their association with silent myocardial ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Oxidative Stress and Diabetic Complications

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.

1 reference

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10 September 2017

Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Immune and inflammatory mechanisms of atherosclerosis (*)

1 reference

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10 September 2017

Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Mitochondria-targeted antioxidants in the treatment of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Role of mitochondrial dysfunction in insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

1 reference

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10 September 2017

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

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10 September 2017

Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation

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10 September 2017

Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Inflammation in atherosclerosis

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10 September 2017

Mitochondria-targeted antioxidants protect pancreatic β-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094376

10 September 2017

Mitochondrially targeted compounds and their impact on cellular bioenergetics

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14 September 2017

Infectious emergencies in patients with diabetes mellitus.

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14 September 2017

Is glycemic control modulating endoplasmic reticulum stress in leukocytes of type 2 diabetic patients?

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15 June 2018

Is myeloperoxidase a key component in the ROS-induced vascular damage related to nephropathy in type 2 diabetes?

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15 June 2018

NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X

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15 June 2018

The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice.

1 reference

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21 August 2018

Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients.

1 reference

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21 August 2018

Is antioxidant potential of the mitochondrial targeted ubiquinone derivative MitoQ conserved in cells lacking mtDNA?

1 reference

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21 August 2018

Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study

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21 August 2018

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

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2 December 2018

Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/27810734

12 December 2020

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Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice

1 reference

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12 December 2020

based on heuristic

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Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/27810734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial Dysfunction, Obesity and Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/27810734

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/27810734

12 December 2020

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inferred from PubMed ID database lookup

Complex I dysfunction and tolerance to nitroglycerin: an approach based on mitochondrial-targeted antioxidants

1 reference

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12 December 2020

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Identifiers

10.1016/J.REDOX.2016.10.017

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Europe PubMed Central

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4 June 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27810734%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27810734%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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