Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. (Q39173934)

9 September 2017

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. (English)

1 reference

9 September 2017

1 reference

1 reference

9 September 2017

1 reference

9 September 2017

Maria Vinci

0 references

Imelda M McGonnell

0 references

Chris Jones

0 references

Rui M Reis

0 references

Alan Ashworth

1 reference

9 September 2017

Paul Workman

1 reference

9 September 2017

Ilirjana Bajrami

1 reference

9 September 2017

Alexa Jury

1 reference

9 September 2017

Lynn Bjerke

1 reference

9 September 2017

Alan Mackay

1 reference

9 September 2017

Meera Nandhabalan

1 reference

9 September 2017

Anna Burford

1 reference

9 September 2017

Sergey Popov

1 reference

9 September 2017

Dorine A Bax

1 reference

9 September 2017

Diana Carvalho

1 reference

9 September 2017

Kathryn R Taylor

1 reference

9 September 2017

1 May 2013

1 reference

9 September 2017

1 reference

9 September 2017

1 reference

9 September 2017

1 reference

9 September 2017

512-519

1 reference

describes a project that uses

9 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3763966/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Paediatric and adult malignant glioma: close relatives or distant cousins?

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Understanding the language of Lys36 methylation at histone H3.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Spatio-temporal transcriptome of the human brain

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Subtypes of medulloblastoma have distinct developmental origins

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Myc proteins as therapeutic targets

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Function of RNA-binding protein Musashi-1 in stem cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Developmental functions of the Distal-less/Dlx homeobox genes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Defective limbic system in mice lacking the tailless gene

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Transcriptional regulation of cortical neuron migration by POU domain factors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

There's a time and a place for MYCN.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763966

10.1158/2159-8290.CD-12-0426

21 August 2018

Identifiers

DOI

1 reference

9 September 2017

1 reference

9 September 2017

PubMed publication ID

23539269

1 reference