Expression of the Adenovirus Early Gene 1A Transcription-Repression Domain Alone Downregulates HER2 and Results in the Death of Human Breast Cancer Cells Upregulated for the HER2 Proto-Oncogene (Q39172262)

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scientific article published on July 2011

Language	Label	Description	Also known as
English	Expression of the Adenovirus Early Gene 1A Transcription-Repression Domain Alone Downregulates HER2 and Results in the Death of Human Breast Cancer Cells Upregulated for the HER2 Proto-Oncogene	scientific article published on July 2011

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Expression of the Adenovirus Early Gene 1A Transcription-Repression Domain Alone Downregulates HER2 and Results in the Death of Human Breast Cancer Cells Upregulated for the HER2 Proto-Oncogene (English)

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

1 reference

based on heuristic

inferred from title

author name string

Paul M Loewenstein

1

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Maurice Green

2

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

publication date

1 July 2011

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

737-744

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

Principles of cancer therapy: oncogene and non-oncogene addiction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Oncogene addiction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Adenovirus E1A proteins are closely associated with chromatin in productively infected and transformed cells

1 reference

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10 September 2017

Targeting the function of the HER2 oncogene in human cancer therapeutics

1 reference

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10 September 2017

The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis

1 reference

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The role of ErbB inhibitors in trastuzumab resistance

1 reference

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 reference

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Adenovirus E1A N-terminal amino acid sequence requirements for repression of transcription in vitro and in vivo correlate with those required for E1A interference with TBP-TATA complex formation

1 reference

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Essential role for oncogenic Ras in tumour maintenance

1 reference

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Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

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10 September 2017

The adenovirus E1A repression domain disrupts the interaction between the TATA binding protein and the TATA box in a manner reversible by TFIIB.

1 reference

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Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat

1 reference

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10 September 2017

Transcriptional repression by human adenovirus E1A N terminus/conserved domain 1 polypeptides in vivo and in vitro in the absence of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Transcription factor TFIID is a direct functional target of the adenovirus E1A transcription-repression domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

1 reference

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Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

1 reference

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Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

10 September 2017

Mutational and functional analysis of an essential subdomain of the adenovirus E1A N-terminal transcription repression domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

14 September 2017

Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines.

1 reference

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14 September 2017

Identification of a minimal c-erbB-2 promoter region that mediates preferential expression of a linked foreign gene in human breast cancer cells.

1 reference

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25 September 2017

EGFR antisense RNA blocks expression of the epidermal growth factor receptor and partially reverse the malignant phenotype of human breast cancer MDA-MB-231 cells

1 reference

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25 September 2017

Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

25 September 2017

Functional domains of adenovirus type 5 E1a proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

17 June 2018

Repressed expression of the HER-2/c-erbB-2 proto-oncogene by the adenovirus E1a gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

17 June 2018

Human adenoviruses: propagation, purification, quantification, and storage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

21 August 2018

The transcription-repression domain of the adenovirus E1A oncoprotein targets p300 at the promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

21 August 2018

Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

21 August 2018

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218411

21 August 2018

An adenovirus E1A protein domain activates transcription in vivo and in vitro in the absence of protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Herceptin, a monoclonal humanized antibody anti-HER2: a major therapeutic progress in breast cancers overexpressing this oncogene?]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/1947601911426570

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 September 2017

ResearchGate publication ID

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