Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein. (Q39179854)

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scientific article published on 14 November 2016

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English	Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein.	scientific article published on 14 November 2016

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scholarly article

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27 March 2020

Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein (English)

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27 March 2020

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27 March 2020

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Lei Jiang

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27 March 2020

Adam Boufersaoui

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27 March 2020

Chendong Yang

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27 March 2020

Bookyung Ko

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27 March 2020

Dinesh Rakheja

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Gerardo Guevara

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27 March 2020

Ralph J DeBerardinis

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14 November 2016

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27 March 2020

Metabolic Engineering

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27 March 2020

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Pt B

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198-207

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27 March 2020

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion Syndrome

1 reference

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1 reference

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Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

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1 reference

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1 reference

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Oncometabolites: linking altered metabolism with cancer

1 reference

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Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria

1 reference

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The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis

1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5429990

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5429990

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5429990

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/27856334

12 December 2020

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10.1016/J.YMBEN.2016.11.004

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27 March 2020

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