Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells (Q39132731)

9 September 2017

title

Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells (English)

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9 September 2017

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Sun-Mi Yun

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9 September 2017

Ji Hoon Jung

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9 September 2017

Soo-Jin Jeong

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9 September 2017

Eun Jung Sohn

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9 September 2017

Bonglee Kim

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9 September 2017

Sung-Hoon Kim

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9 September 2017

publication date

27 June 2013

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9 September 2017

published in

Phytotherapy Research

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9 September 2017

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9 September 2017

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9 September 2017

page(s)

458-464

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The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells

9 September 2017

cites work

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Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells

21 January 2018

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Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231.

21 January 2018

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Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway.

21 January 2018

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Cardiovascular effects of Danshen

21 January 2018

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Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β.

21 January 2018

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Molecular mechanisms of inhibitory activities of tanshinones on lipopolysaccharide-induced nitric oxide generation in RAW 264.7 cells.

21 January 2018

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Control of the autophagy maturation step by the MAPK ERK and p38: lessons from environmental carcinogens

21 January 2018

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Growth-inhibiting and apoptosis-inducing effects of Tanshinone II A on human gastric carcinoma cells

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells

21 January 2018

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Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle cell migration and MMP-9 activity through AKT signaling pathway

21 January 2018

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Cryptotanshinone enhances TNF-α-induced apoptosis in chronic myeloid leukemia KBM-5 cells

21 January 2018

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LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization

21 January 2018

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Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics

21 January 2018

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Crosstalk between apoptosis and autophagy within the Beclin 1 interactome

21 January 2018

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Anti-glioma action of aloe emodin: the role of ERK inhibition.

21 January 2018

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Autophagy fights disease through cellular self-digestion

21 January 2018

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Pathways of apoptotic and non-apoptotic death in tumour cells

21 January 2018

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Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy

21 January 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

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Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

21 January 2018

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Extracellular signal-regulated kinase as an inducer of non-apoptotic neuronal death

21 January 2018

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Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

21 January 2018

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21 January 2018

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Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells.

21 January 2018

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Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro

21 January 2018

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AMP-activated protein kinase and cancer

21 January 2018

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Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells.

21 January 2018

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An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival

21 January 2018

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Effects of tanshinone IIA on the hepatotoxicity and gene expression involved in alcoholic liver disease

21 January 2018

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Protective effect of Salvia miltiorrhizae injection on N(G)-nitro-D-arginine induced nitric oxide deficient and oxidative damage in rat kidney

21 January 2018

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Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells

21 January 2018

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Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling

21 January 2018

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Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PTR.5015

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release_tlwiidgqwngazfgpf7umqe3h5u

9 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/tlwiidgqwngazfgpf7umqe3h5u

mapped directly with Wikidata item

24 November 2022

based on heuristic

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