FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage (Q39062387)

8 September 2017

title

FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage (English)

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Transformation related protein 53

8 September 2017

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Transformed mouse 3T3 cell double minute 2

GOA release 2020-03-11

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DNA segment, Chr 7, ERATO Doi 443, expressed

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

S Yan

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8 September 2017

L Qiu

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8 September 2017

K Ma

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8 September 2017

X Zhang

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8 September 2017

Y Zhao

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8 September 2017

J Zhang

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8 September 2017

X Li

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8 September 2017

X Hao

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8 September 2017

Z Li

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8 September 2017

language of work or name

English

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publication date

18 November 2013

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8 September 2017

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8 September 2017

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8 September 2017

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8 September 2017

page(s)

5424-5433

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Physiological functions of the HECT family of ubiquitin ligases

8 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FONC.2013.494

Modification of proteins by ubiquitin and ubiquitin-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Proteasome-independent functions of ubiquitin in endocytosis and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Polyubiquitin chains: polymeric protein signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

The multiple levels of regulation by p53 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Mdm2 promotes the rapid degradation of p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.494

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Acetylation is indispensable for p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

The ubiquitin ligase COP1 is a critical negative regulator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Making sense of ubiquitin ligases that regulate p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

21 January 2018

Chromosome fragile sites

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Common fragile sites: genomic hotspots of DNA damage and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

An HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

FATS is a transcriptional target of p53 and associated with antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

FATS expression is associated with cisplatin sensitivity in non small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Genomic instability in radiation-induced mouse lymphoma from p53 heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Regulation of p53 localization and activity by Ubc13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Blinded by the Light: The Growing Complexity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Building ubiquitin chains: E2 enzymes at work

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

The adenoviral E1A induces p21WAF1/CIP1 expression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Adenoviral E1A targets Mdm4 to stabilize tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

Ubiquitin signalling in DNA replication and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.494

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.494

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release_cvicvubftfge5o4xpum6ts5il4

8 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cvicvubftfge5o4xpum6ts5il4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference