Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise (Q39010502)

3 March 2018

review article

1 reference

title

Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise (English)

1 reference

3 March 2018

protein-protein interaction

main subject

1 reference

Sarah Loerch

0 references

Clara L Kielkopf

0 references

language of work or name

English

0 references

publication date

1 December 2016

1 reference

3 March 2018

published in

RNA

1 reference

3 March 2018

volume

1 reference

3 March 2018

issue

1 reference

3 March 2018

page(s)

1795-1807

1 reference

3 March 2018

Molecular architecture of the Saccharomyces cerevisiae activated spliceosome

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Dividing and Conquering the Family of RNA Recognition Motifs: A Representative Case Based on hnRNP L.

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The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein

17 June 2018

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MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis

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Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

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Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

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17 June 2018

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U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing

17 June 2018

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Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex

17 June 2018

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A Novel Protein-Protein Interaction in the RES (REtention and Splicing) Complex

17 June 2018

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A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

17 June 2018

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Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution

17 June 2018

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Cancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary Complex

17 June 2018

1 reference

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Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri ORF57 to the Mammalian Export Adaptor ALYREF

17 June 2018

1 reference

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Phosphorylation-mediated regulation of alternative splicing in cancer

17 June 2018

1 reference

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Modulation of allostery by protein intrinsic disorder

17 June 2018

1 reference

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Regulation of splicing by SR proteins and SR protein-specific kinases

17 June 2018

1 reference

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Structure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor Complex

17 June 2018

1 reference

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Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition

17 June 2018

1 reference

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The spliceosome as a target of novel antitumour drugs

17 June 2018

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The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice.

17 June 2018

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Dynamic protein-protein interaction wiring of the human spliceosome

17 June 2018

1 reference

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Three RNA recognition motifs participate in RNA recognition and structural organization by the pro-apoptotic factor TIA-1.

17 June 2018

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Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

17 June 2018

1 reference

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Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells

17 June 2018

1 reference

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CAPER-α alternative splicing regulates the expression of vascular endothelial growth factor₁₆₅ in Ewing sarcoma cells

17 June 2018

1 reference

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Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins

17 June 2018

1 reference

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Structural Basis for the Recognition of Cellular mRNA Export Factor REF by Herpes Viral Proteins HSV-1 ICP27 and HVS ORF57

17 June 2018

1 reference

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Phospho.ELM: a database of phosphorylation sites--update 2011

17 June 2018

1 reference

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17 June 2018

1 reference

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The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selection

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1 reference

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17 June 2018

1 reference

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17 June 2018

1 reference

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Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60

17 June 2018

1 reference

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1 reference

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Different requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors.

17 June 2018

1 reference

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Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

17 June 2018

1 reference

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U2AF-homology motif interactions are required for alternative splicing regulation by SPF45

17 June 2018

1 reference

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Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65)

17 June 2018

1 reference

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Structure and interactions of the first three RNA recognition motifs of splicing factor prp24

17 June 2018

1 reference

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Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit

17 June 2018

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17 June 2018

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17 June 2018

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Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.

17 June 2018

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17 June 2018

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Crystal structure of a core spliceosomal protein interface

17 June 2018

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Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65.

17 June 2018

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Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors

17 June 2018

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17 June 2018

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The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression

17 June 2018

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Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta

17 June 2018

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The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

17 June 2018

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MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.

17 June 2018

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Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

17 June 2018

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U2AF homology motifs: protein recognition in the RRM world

17 June 2018

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Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence

17 June 2018

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The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

17 June 2018

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Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d

17 June 2018

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U1A RNA-binding domain at 1.8 A resolution

17 June 2018

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Structure of the Y14-Magoh core of the exon junction complex

17 June 2018

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Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.

17 June 2018

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17 June 2018

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Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP

17 June 2018

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Crystal structure of theDrosophilaMago nashi–Y14 complex

17 June 2018

1 reference

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Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1

17 June 2018

1 reference

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Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45

17 June 2018

1 reference

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Molecular cloning and characterization of CAPER, a novel coactivator of activating protein-1 and estrogen receptors

17 June 2018

1 reference

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A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer

17 June 2018

1 reference

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A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

17 June 2018

1 reference

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17 June 2018

1 reference

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The FBP interacting repressor targets TFIIH to inhibit activated transcription

17 June 2018

1 reference

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Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans

17 June 2018

1 reference

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Functional recognition of the 3' splice site AG by the splicing factor U2AF35.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

PUF60: a novel U2AF65-related splicing activity

17 June 2018

1 reference

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Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly

17 June 2018

1 reference

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Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA

17 June 2018

1 reference

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A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site

17 June 2018

1 reference

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Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells

17 June 2018

1 reference

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Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis

17 June 2018

1 reference

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Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects

17 June 2018

1 reference

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Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

A cDNA clone of the hnRNP C proteins and its homology with the single-stranded DNA binding protein UP2

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: domain structure and expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Cloning and domain structure of the mammalian splicing factor U2AF

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Structural Analysis of the Smad2−MAN1 Interaction That Regulates Transforming Growth Factor-β Signaling at the Inner Nuclear Membrane

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

Intron Removal Requires Proofreading of U2AF/3' Splice Site Recognition by DEK

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5113200

PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27852923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fast approximate motif statistics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27852923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The SF3b155 N-terminal domain is a scaffold important for splicing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27852923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.057950.116

1 reference

3 March 2018

PMC publication ID

5113200

1 reference

3 March 2018

PubMed publication ID

27852923

1 reference

3 March 2018