Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment. (Q38980782)

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21 March 2020

title

Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment (English)

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21 March 2020

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21 March 2020

Ze Liu

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21 March 2020

Min Xiong

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21 March 2020

Yan Zhang

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21 March 2020

Nan Bai

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21 March 2020

Yunping Luo

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21 March 2020

Luyuan Li

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21 March 2020

Yuquan Wei

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21 March 2020

Yanhua Liu

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21 March 2020

Xiaoyue Tan

1 reference

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21 March 2020

Rong Xiang

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21 March 2020

language of work or name

English

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publication date

27 June 2014

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21 March 2020

published in

Nature Communications

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21 March 2020

volume

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21 March 2020

page(s)

4280

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Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment

21 March 2020

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Progress in microRNA delivery

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Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting

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Cell-penetrating peptides: breaking through to the other side

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Liposome formulated with TAT-modified cholesterol for improving brain delivery and therapeutic efficacy on brain glioma in animals.

21 January 2018

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Size-controlled, dual-ligand modified liposomes that target the tumor vasculature show promise for use in drug-resistant cancer therapy

21 January 2018

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A new peptide motif present in the protective antigen of anthrax toxin exerts its efficiency on the cellular uptake of liposomes and applications for a dual-ligand system.

21 January 2018

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Integrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administration

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The tumor microenvironment: a target for combination therapy of breast cancer

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CSF-1R inhibition alters macrophage polarization and blocks glioma progression

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Selective ablation of tumor-associated macrophages suppresses metastasis and angiogenesis

21 January 2018

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Targeting tumor-associated macrophages as a novel strategy against breast cancer

21 January 2018

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A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis

21 January 2018

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Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis

21 January 2018

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Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation

21 January 2018

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Asparagine endopeptidase is required for normal kidney physiology and homeostasis

21 January 2018

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Peptide-based MRI contrast agent and near-infrared fluorescent probe for intratumoral legumain detection

21 January 2018

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Effects of legumain as a potential prognostic factor on gastric cancers

21 January 2018

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Synthetic enzyme inhibitor: a novel targeting ligand for nanotherapeutic drug delivery inhibiting tumor growth without systemic toxicity

21 January 2018

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Functional imaging of legumain in cancer using a new quenched activity-based probe

21 January 2018

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Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug

21 January 2018

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The Legumain Protease‐Activated Auristatin Prodrugs Suppress Tumor Growth and Metastasis without Toxicity

21 January 2018

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Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms

21 January 2018

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A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain

21 January 2018

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Current trends in the use of liposomes for tumor targeting

21 January 2018

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Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery

21 January 2018

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Cationic TAT peptide transduction domain enters cells by macropinocytosis.

21 January 2018

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Alginic acid-coated chitosan nanoparticles loaded with legumain DNA vaccine: effect against breast cancer in mice

21 January 2018

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Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones

21 January 2018

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Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases

21 January 2018

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Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis

21 January 2018

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Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens

21 January 2018

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Aza-peptidyl Michael acceptor and epoxide inhibitors--potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases).

21 January 2018

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Design and Synthesis of Novel Functional Lipid-Based Bioconjugates for Drug Delivery and Other Applications

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5280

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS5280

1 reference

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Dimensions Publication ID

21 March 2020

ADS bibcode

2014NatCo...5.4280L

0 references

1038857601

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1 reference

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