DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells (Q38984711)

8 September 2017

title

DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells (English)

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8 September 2017

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Yegor Smurnyy

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8 September 2017

Mi Cai

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8 September 2017

Hua Wu

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8 September 2017

Elizabeth McWhinnie

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8 September 2017

John A Tallarico

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8 September 2017

Yi Yang

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8 September 2017

Yan Feng

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8 September 2017

publication date

15 June 2014

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8 September 2017

published in

Nature Chemical Biology

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8 September 2017

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8 September 2017

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8 September 2017

page(s)

623-625

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

8 September 2017

cites work

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Genome engineering using the CRISPR-Cas9 system

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

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XPB, a subunit of TFIIH, is a target of the natural product triptolide.

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Triptolide directly inhibits dCTP pyrophosphatase.

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Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease

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TAB1: a target of triptolide in macrophages

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Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair

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p52 Mediates XPB function within the transcription/repair factor TFIIH.

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Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair.

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Chemically defined conditions for human iPSC derivation and culture

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

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Optimization of scarless human stem cell genome editing

21 January 2018

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In vivo genome editing using a high-efficiency TALEN system

21 January 2018

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KBM-7, a human myeloid leukemia cell line with double Philadelphia chromosomes lacking normal c-ABL and BCR transcripts.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24929529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24929529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1550

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Dimensions Publication ID

8 September 2017

1019333267

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