Epigenetics in Multiple Myeloma. (Q38970577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

review article

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title

Epigenetics in Multiple Myeloma (English)

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24 March 2020

1 reference

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24 March 2020

Juliette M C Bouyssou

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Irene M Ghobrial

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Siobhan V Glavey

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24 March 2020

Salomon Manier

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Antonio Sacco

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Karma Salem

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

Aldo M Roccaro

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24 March 2020

publication date

1 January 2016

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Cancer Treatment and Research

24 March 2020

published in

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24 March 2020

volume

169

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24 March 2020

page(s)

35-49

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Multiple myeloma: evolving genetic events and host interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Characterization of clonogenic multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

DNA methylation patterns and epigenetic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

21 January 2018

Epigenetics in cancer

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Global epigenetic regulation of microRNAs in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNAs: small RNAs with a big role in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

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MicroRNA control of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

A microRNA polycistron as a potential human oncogene

21 January 2018

1 reference

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Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA expression in lymphoid malignancies: new hope for diagnosis and therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNAs: New Players in Multiple Myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Clinical and biologic implications of recurrent genomic aberrations in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Targeting NF-kappaB in Waldenstrom macroglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

A VEGF-dependent autocrine loop mediates proliferation and capillarogenesis in bone marrow endothelial cells of patients with multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Expression profile of mammalian microRNAs in endometrioid adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Noncoding RNAs and chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Molecular sequelae of histone deacetylase inhibition in human malignant B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Adhesion molecules--The lifelines of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Current and potential epigenetic targets in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Treatment of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

The fundamental role of epigenetic events in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

DNA methylation changes in multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Histone deacetylase inhibitors in the treatment for multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Panobinostat approved for multiple myeloma

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-40320-5_4

10.1007/978-3-319-40320-5_4

31 March 2020

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27696257%20AND%20SRC:MED&resulttype=core&format=json