What is the evidence base for atopic eczema treatments? A summary of published randomized controlled trials. (Q38933737)

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21 March 2020

review article

1 reference

title

What is the evidence base for atopic eczema treatments? A summary of published randomized controlled trials (English)

1 reference

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21 March 2020

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21 March 2020

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21 March 2020

H Nankervis

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21 March 2020

F M Delamere

1 reference

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21 March 2020

S Smith

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21 March 2020

N K Rogers

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21 March 2020

H C Williams

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21 March 2020

language of work or name

English

0 references

publication date

5 March 2017

1 reference

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British Journal of Dermatology

21 March 2020

published in

1 reference

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21 March 2020

volume

176

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21 March 2020

issue

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21 March 2020

page(s)

910-927

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The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions

21 March 2020

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Onset of action of pimecrolimus cream 1% in the treatment of atopic eczema in infants

21 January 2018

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Effect of pimecrolimus cream 1% on skin condition and sleep disturbance in children with atopic dermatitis

21 January 2018

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Skin physiological parameters confirm the therapeutic efficacy of pimecrolimus cream 1% in patients with mild-to-moderate atopic dermatitis

21 January 2018

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Two topical calcineurin inhibitors for the treatment of atopic dermatitis in pediatric patients: a meta-analysis of randomized clinical trials

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Treatment of lichenified atopic eczema with tacrolimus ointment

21 January 2018

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Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis.

21 January 2018

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0.03% Tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: results of a randomized double-blind controlled trial

21 January 2018

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Superiority of tacrolimus 0.1% ointment compared with fluticasone 0.005% in adults with moderate to severe atopic dermatitis of the face: results from a randomized, double-blind trial.

21 January 2018

1 reference

Tacrolimus ointment is more effective than pimecrolimus cream with a similar safety profile in the treatment of atopic dermatitis: results from 3 randomized, comparative studies

21 January 2018

1 reference

A randomized investigator-blinded study comparing pimecrolimus cream 1% with tacrolimus ointment 0.03% in the treatment of pediatric patients with moderate atopic dermatitis

21 January 2018

1 reference

Pharmacokinetics of topical calcineurin inhibitors in adult atopic dermatitis: a randomized, investigator-blind comparison.

21 January 2018

1 reference

Reduction of relapses of atopic dermatitis with methylprednisolone aceponate cream twice weekly in addition to maintenance treatment with emollient: a multicentre, randomized, double-blind, controlled study

21 January 2018

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Intermittent dosing of fluticasone propionate cream for reducing the risk of relapse in atopic dermatitis patients

21 January 2018

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Twice weekly fluticasone propionate added to emollient maintenance treatment to reduce risk of relapse in atopic dermatitis: randomised, double blind, parallel group study

21 January 2018

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Efficacy and safety of fluticasone propionate 0.005% ointment in the long-term maintenance treatment of children with atopic dermatitis: differences between boys and girls?

21 January 2018

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Intermittent therapy for flare prevention and long-term disease control in stabilized atopic dermatitis: a randomized comparison of 3-times-weekly applications of tacrolimus ointment versus vehicle

21 January 2018

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Proactive disease management with 0.03% tacrolimus ointment for children with atopic dermatitis: results of a randomized, multicentre, comparative study

21 January 2018

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Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment

21 January 2018

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A randomized, open-label, multicenter trial of topical tacrolimus for the treatment of pruritis in patients with atopic dermatitis

21 January 2018

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Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis

21 January 2018

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Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.

21 January 2018

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Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial

21 January 2018

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Off-label use of azathioprine in dermatology: a systematic review

21 January 2018

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Narrow-band ultraviolet B and broad-band ultraviolet A phototherapy in adult atopic eczema: a randomised controlled trial.

21 January 2018

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Narrowband UVB phototherapy in skin conditions beyond psoriasis.

21 January 2018

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MAS063DP is effective monotherapy for mild to moderate atopic dermatitis in infants and children: a multicenter, randomized, vehicle-controlled study

21 January 2018

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Evaluation of a parental training program for the management of childhood atopic dermatitis.

21 January 2018

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Pediatric atopic eczema: the impact of an educational intervention.

21 January 2018

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21 January 2018

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Topical corticosteroids for atopic eczema: clinical and cost effectiveness of once-daily vs. more frequent use.

21 January 2018

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Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial

21 January 2018

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Short-term effects of topical fusidic acid or mupirocin on the prevalence of fusidic acid resistant (FusR) Staphylococcus aureus in atopic eczema

21 January 2018

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A randomized, double-blind study to assess the efficacy of addition of tetracycline to triamcinolone acetonide in the treatment of moderate to severe atopic dermatitis

21 January 2018

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21 January 2018

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21 January 2018

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Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis

21 January 2018

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21 January 2018

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No effects of probiotics on atopic dermatitis in infancy: a randomized placebo-controlled trial.

21 January 2018

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Prospective, randomized controlled trial on Lactobacillus rhamnosus in infants with moderate to severe atopic dermatitis

21 January 2018

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21 January 2018

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21 January 2018

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Effects of Lactobacillus salivarius LS01 (DSM 22775) treatment on adult atopic dermatitis: a randomized placebo-controlled study

21 January 2018

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Treatment and secondary prevention effects of the probiotics Lactobacillus paracasei or Bifidobacterium lactis on early infant eczema: randomized controlled trial with follow-up until age 3 years

21 January 2018

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21 January 2018

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21 January 2018

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Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial

21 January 2018

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Gamma-linolenic-acid-rich borage seed oil capsules in children with atopic dermatitis. A placebo-controlled double-blind study

21 January 2018

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Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema

21 January 2018

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Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial

21 January 2018

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Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids).

21 January 2018

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Epogam evening primrose oil treatment in atopic dermatitis and asthma

21 January 2018

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A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis

21 January 2018

1 reference

Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial.

21 January 2018

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Efficacy of dietary hempseed oil in patients with atopic dermatitis.

21 January 2018

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A randomised controlled trial of ion-exchange water softeners for the treatment of eczema in children

21 January 2018

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Randomized comparison of the type 4 phosphodiesterase inhibitor cipamfylline cream, cream vehicle and hydrocortisone 17-butyrate cream for the treatment of atopic dermatitis

21 January 2018

1 reference

Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease

21 January 2018

1 reference

Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages

21 January 2018

1 reference

Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

Effect of a Mycobacterium vaccae derivative on paediatric atopic dermatitis: a randomized, controlled trial

21 January 2018

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An evaluation of prescription device moisturizers

21 January 2018

1 reference

Treatment with a barrier-strengthening moisturizing cream delays relapse of atopic dermatitis: a prospective and randomized controlled clinical trial.

21 January 2018

1 reference

Evaluation of efficacy of a skin lipid mixture in patients with irritant contact dermatitis, allergic contact dermatitis or atopic dermatitis: a multicenter study

21 January 2018

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A double-blind study of tolerance and efficacy of a new urea-containing moisturizer in patients with atopic dermatitis

21 January 2018

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A double-blind study comparing the effect of glycerin and urea on dry, eczematous skin in atopic patients

21 January 2018

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A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% urea.

21 January 2018

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New emollient with topical corticosteroid-sparing effect in treatment of childhood atopic dermatitis: SCORAD and quality of life improvement.

21 January 2018

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Natural peroxisome proliferator-activated receptor-alpha agonist cream demonstrates similar therapeutic response to topical steroids in atopic dermatitis

21 January 2018

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Clinical effects of kestose, a prebiotic oligosaccharide, on the treatment of atopic dermatitis in infants.

21 January 2018

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Probiotic supplement reduces atopic dermatitis in preschool children: a randomized, double-blind, placebo-controlled, clinical trial.

21 January 2018

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Lactobacillus salivarius plus fructo-oligosaccharide is superior to fructo-oligosaccharide alone for treating children with moderate to severe atopic dermatitis: a double-blind, randomized, clinical trial of efficacy and safety

21 January 2018

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Efficacy and functionality of silver-coated textiles in patients with atopic eczema.

21 January 2018

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Nurse-led clinics reduce severity of childhood atopic eczema: a review of the literature.

21 January 2018

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Improvement of pruritus and quality of life of children with atopic dermatitis and their families after joining support groups.

21 January 2018

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E-health in caring for patients with atopic dermatitis: a randomized controlled cost-effectiveness study of internet-guided monitoring and online self-management training

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Psychophysiological effects of stress management in patients with atopic dermatitis: a randomized controlled trial.

21 January 2018

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Effect of climatic change in children with atopic eczema.

21 January 2018

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Double-blind placebo-controlled house dust mite control measures in adult patients with atopic dermatitis.

21 January 2018

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Effect of mattress encasings on atopic dermatitis outcome measures in a double-blind, placebo-controlled study: the Dutch mite avoidance study

21 January 2018

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A randomized controlled pilot study of the effects of an extra office visit on adherence and outcomes in atopic dermatitis

21 January 2018

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Eczema workshops reduce severity of childhood atopic eczema

21 January 2018

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Costs and cost-effectiveness analysis of treatment in children with eczema by nurse practitioner vs. dermatologist: results of a randomized, controlled trial and a review of international costs

21 January 2018

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Online video improves clinical outcomes in adults with atopic dermatitis: a randomized controlled trial

21 January 2018

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The clinical efficacy, safety and functionality of anion textile in the treatment of atopic dermatitis

21 January 2018

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Flucloxacillin in the treatment of atopic dermatitis

21 January 2018

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An efficient new formulation of fusidic acid and betamethasone 17-valerate (fucicort lipid cream) for treatment of clinically infected atopic dermatitis

21 January 2018

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Efficacy of crisis intervention treatment with topical corticosteroid prednicarbat with and without partial wet-wrap dressing in atopic dermatitis

21 January 2018

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A randomised study of "wet wraps" versus conventional treatment for atopic eczema

21 January 2018

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The effectiveness of wet wrap dressings using 0.1% mometasone furoate and 0.005% fluticasone proprionate ointments in the treatment of moderate to severe atopic dermatitis in children

21 January 2018

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Topical steroids under wet-wrap dressings in atopic dermatitis--a vehicle-controlled trial

21 January 2018

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Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity.

21 January 2018

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Systemic ketoconazole is an effective treatment of atopic dermatitis with IgE-mediated hypersensitivity to yeasts

21 January 2018

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Systemic ketoconazole for yeast allergic patients with atopic dermatitis

21 January 2018

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Is topical antimycotic treatment useful as adjuvant therapy for flexural atopic dermatitis: randomized, double-blind, controlled trial using one side of the elbow or knee as a control

21 January 2018

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Effect of rosmarinic acid on atopic dermatitis

21 January 2018

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Effects of nonpathogenic gram-negative bacterium Vitreoscilla filiformis lysate on atopic dermatitis: a prospective, randomized, double-blind, placebo-controlled clinical study.

21 January 2018

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Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trial

21 January 2018

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Evaluation of Topical Vitamin B12 for the Treatment of Childhood Eczema

21 January 2018

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Efficacy and safety of topical WBI-1001 in the treatment of atopic dermatitis: results from a phase 2A, randomized, placebo-controlled clinical trial

21 January 2018

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Randomized, parallel-group, double-blind, controlled study to evaluate the efficacy and safety of carbohydrate-derived fulvic acid in topical treatment of eczema

21 January 2018

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Effect of topical heparin and levomenol on atopic dermatitis: a randomized four-arm, placebo-controlled, double-blind clinical study.

21 January 2018

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Efficacy and safety of 15(R/S)-methyl-lipoxin A(4) in topical treatment of infantile eczema

21 January 2018

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Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus

21 January 2018

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A randomized trial of methotrexate versus azathioprine for severe atopic eczema

21 January 2018

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Methotrexate versus cyclosporine in the treatment of severe atopic dermatitis in children: a multicenter experience from Egypt

21 January 2018

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Montelukast in the treatment of children with moderate-to-severe atopic dermatitis: a pilot study

21 January 2018

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The leukotriene antagonist montelukast as a therapeutic agent for atopic dermatitis

21 January 2018

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A double-blind, placebo-controlled trial of montelukast in adult atopic eczema

21 January 2018

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Montelukast treatment of moderate to severe atopic dermatitis in adults: a randomized, double-blind, placebo-controlled trial.

21 January 2018

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Anti-IL-5 recombinant humanized monoclonal antibody (mepolizumab) for the treatment of atopic dermatitis.

21 January 2018

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A randomized controlled evaluator-blinded trial of intravenous immunoglobulin in adults with severe atopic dermatitis.

21 January 2018

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Long-term Efficacy of Intravenous Immunoglobulin Therapy for Moderate to Severe Childhood Atopic Dermatitis

21 January 2018

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Efficacy and tolerability of three different doses of oral pimecrolimus in the treatment of moderate to severe atopic dermatitis: a randomized controlled trial.

21 January 2018

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Recombinant interferon gamma therapy for atopic dermatitis

21 January 2018

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Prednisolone vs. ciclosporin for severe adult eczema. An investigator-initiated double-blind placebo-controlled multicentre trial

21 January 2018

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Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months

21 January 2018

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Chlorpheniramine is no more effective than placebo in relieving the symptoms of childhood atopic dermatitis with a nocturnal itching and scratching component

21 January 2018

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Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study

21 January 2018

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Treatment of itching in atopic eczema with antihistamines with a low sedative profile

21 January 2018

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Differential effects of new-generation H1-receptor antagonists in pruritic dermatoses.

21 January 2018

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Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitis.

21 January 2018

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Prospective, long-term safety evaluation of the H1-receptor antagonist cetirizine in very young children with atopic dermatitis. ETAC Study Group. Early Treatment of the Atopic Child.

21 January 2018

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The antipruritic effect of a sedative and a non-sedative antihistamine in atopic dermatitis

21 January 2018

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Efficacy and acceptability of a new topical skin lotion of sodium cromoglicate (Altoderm) in atopic dermatitis in children aged 2-12 years: a double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

Efficacy of oral naltrexone on pruritus in atopic eczema: a double-blind, placebo-controlled study.

21 January 2018

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Randomized, double-blind, placebo-controlled trial of autologous blood therapy for atopic dermatitis

21 January 2018

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Full‐spectrum light phototherapy for atopic dermatitis

21 January 2018

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Excimer laser vs. clobetasol propionate 0·05% ointment in prurigo form of atopic dermatitis: a randomized controlled trial, a pilot

21 January 2018

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Effects of nitrazepam on nocturnal scratching in adults with atopic dermatitis: a double-blind placebo-controlled crossover study

21 January 2018

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Efficacy of a 5-HT1a receptor agonist in atopic dermatitis

21 January 2018

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Chinese herbal medicine research in eczema treatment

21 January 2018

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The Efficacy and Safety of a Chinese Herbal Product (Xiao-Feng-San) for the Treatment of Refractory Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Trial

21 January 2018

1 reference

The effect of TJ-15 plus TJ-17 on atopic dermatitis: a pilot study based on the principle of pattern identification

21 January 2018

1 reference

Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis

21 January 2018

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A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis

21 January 2018

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Atopic dermatitis symptoms decreased in children following massage therapy

21 January 2018

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Action of a silk fabric treated with AEGIS in children with atopic dermatitis: a 3-month trial

21 January 2018

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A randomized double-blind study to investigate the clinical efficacy of adding a non-migrating antimicrobial to a special silk fabric in the treatment of atopic dermatitis

21 January 2018

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Probiotics Reduce Gut Microbial Translocation and Improve Adult Atopic Dermatitis

21 January 2018

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Treatment of atopic dermatitis: A comparison of psychological and dermatological approaches to relapse prevention

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BJD.14999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547965%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

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