Real-time dynamic modelling for the design of a cluster-randomized phase 3 Ebola vaccine trial in Sierra Leone. (Q38929731)

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3 April 2020

title

Real-time dynamic modelling for the design of a cluster-randomized phase 3 Ebola vaccine trial in Sierra Leone (English)

1 reference

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2014 Ebola virus epidemic in Sierra Leone

3 April 2020

main subject

phase III clinical trial

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Ebola vaccine

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Orthoebolavirus zairense

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3 April 2020

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W J Edmunds

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3 April 2020

A J Kucharski

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N Goeyvaerts

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A Vandebosch

series ordinal

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R Mogg

series ordinal

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T Vangeneugden

series ordinal

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language of work or name

English

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publication date

23 December 2016

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3 April 2020

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volume

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issue

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page(s)

544-551

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West African Ebola epidemic after one year--slowing but not yet under control

3 April 2020

cites work

1 reference

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7 January 2021

1 reference

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Temporal Changes in Ebola Transmission in Sierra Leone and Implications for Control Requirements: a Real-time Modelling Study

7 January 2021

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Ebola virus disease in West Africa--the first 9 months of the epidemic and forward projections

7 January 2021

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Estimating the probability of demonstrating vaccine efficacy in the declining Ebola epidemic: a Bayesian modelling approach.

7 January 2021

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Potential for large outbreaks of Ebola virus disease

7 January 2021

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Measuring the impact of Ebola control measures in Sierra Leone

7 January 2021

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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

7 January 2021

1 reference

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Simulation-guided phase 3 trial design to evaluate vaccine effectiveness to prevent Ebola virus disease infection: Statistical considerations, design rationale, and challenges

7 January 2021

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Statistical power and validity of Ebola vaccine trials in Sierra Leone: a simulation study of trial design and analysis

7 January 2021

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Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial

7 January 2021

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Understanding the dynamics of Ebola epidemics

7 January 2021

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Transmission dynamics of Ebola virus disease and intervention effectiveness in Sierra Leone

7 January 2021

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Seven challenges for model-driven data collection in experimental and observational studies.

7 January 2021

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Optimal design of studies of influenza transmission in households. I: case-ascertained studies.

7 January 2021

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Optimal design of studies of influenza transmission in households. II: comparison between cohort and case-ascertained studies

7 January 2021

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HPTN 071 (PopART): a cluster-randomized trial of the population impact of an HIV combination prevention intervention including universal testing and treatment: mathematical model

7 January 2021

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Estimation of vaccine efficacy in a repeated measures study under heterogeneity of exposure or susceptibility to infection

7 January 2021

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Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials

7 January 2021

1 reference

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Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths

7 January 2021

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Bayesian modelling of hunting data may improve the understanding of host-parasite systems: wild boar diseases and vaccination as an example.

7 January 2021

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Timing of bacterial carriage sampling in vaccine trials: a modelling study

7 January 2021

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10.1016/J.VACCINE.2016.12.019

7 January 2021

Identifiers

DOI

1 reference

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3 April 2020

1 reference

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