(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels (Q38906824)

7 September 2017

title

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels (English)

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7 September 2017

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7 September 2017

David J Beech

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Mathias Christmann

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Slava Ziegler

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Yasemin Akbulut

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7 September 2017

Hannah J Gaunt

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7 September 2017

Katsuhiko Muraki

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7 September 2017

Melanie J Ludlow

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7 September 2017

Mohamed S Amer

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7 September 2017

Alexander Bruns

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7 September 2017

Naveen S Vasudev

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7 September 2017

Lea Radtke

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7 September 2017

Matthieu Willot

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7 September 2017

Sven Hahn

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7 September 2017

Tobias Seitz

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7 September 2017

language of work or name

English

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publication date

23 February 2015

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Angewandte Chemie International Edition

7 September 2017

published in

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volume

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7 September 2017

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7 September 2017

page(s)

3787-3791

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Renal cancer: oxygen meets metabolism

7 September 2017

cites work

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Biology-oriented synthesis

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Nature's contribution to today's pharmacopeia.

21 January 2018

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Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri.

21 January 2018

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Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile

21 January 2018

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Englerin a selectively induces necrosis in human renal cancer cells

21 January 2018

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Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality

21 January 2018

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Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

21 January 2018

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Total synthesis and absolute configuration of the guaiane sesquiterpene englerin A.

21 January 2018

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Enantioselective synthesis of (-)-englerins A and B.

21 January 2018

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Total synthesis of englerin A.

21 January 2018

1 reference

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Enantioselective formal synthesis of (-)-englerin A via a Rh-catalyzed [4 + 3] cycloaddition reaction

21 January 2018

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Asymmetric, protecting-group-free total synthesis of (-)-englerin A.

21 January 2018

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A brief synthesis of (-)-englerin A.

21 January 2018

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Chemical synthesis of the englerins.

21 January 2018

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Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma.

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Physiology and pathophysiology of canonical transient receptor potential channels

21 January 2018

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In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels -- mirage or pot of gold?

21 January 2018

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Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.

21 January 2018

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TRPC channel activation by extracellular thioredoxin

21 January 2018

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Isoform- and receptor-specific channel property of canonical transient receptor potential (TRPC)1/4 channels

21 January 2018

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Characteristics of transient receptor potential canonical calcium-permeable channels and their relevance to vascular physiology and disease

21 January 2018

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Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels

21 January 2018

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TRPC1 and TRPC5 form a novel cation channel in mammalian brain.

21 January 2018

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Conserved gating elements in TRPC4 and TRPC5 channels

21 January 2018

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Generation of functional ion-channel tools by E3 targeting.

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25707820

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/ANIE.201411511

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Dimensions Publication ID

7 September 2017

Altmetric DOI

10.1002/ANIE.201411511

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1033375856

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PMC publication ID

7116557

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1 reference