Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer (Q38895940)

7 September 2017

Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer (English)

1 reference

7 September 2017

1 reference

1 reference

1 reference

Aimalie L Hardaway

1 reference

7 September 2017

Mackenzie K Herroon

series ordinal

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7 September 2017

Erandi Rajagurubandara

series ordinal

1 reference

7 September 2017

Izabela Podgorski

series ordinal

1 reference

7 September 2017

24 March 2015

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Clinical & Experimental Metastasis

7 September 2017

1 reference

7 September 2017

1 reference

7 September 2017

1 reference

7 September 2017

353-368

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describes a project that uses

7 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4393805/fullTextXML

inferred from PubMed Central ID database lookup

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Managing bone metastases and reducing skeletal related events in prostate cancer

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9 September 2017

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Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases

9 September 2017

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9 September 2017

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Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms

9 September 2017

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9 September 2017

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Determinants of bone marrow adiposity: the modulation of peroxisome proliferator-activated receptor-γ2 activity as a central mechanism.

9 September 2017

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Biologic therapies and systemic bone loss in rheumatoid arthritis.

9 September 2017

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Neutralizing tumor-promoting chronic inflammation: a magic bullet?

9 September 2017

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A CXCL1 paracrine network links cancer chemoresistance and metastasis

9 September 2017

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The role of CXC chemokines and their receptors in the progression and treatment of tumors

9 September 2017

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Genes associate with abnormal bone cell activity in bone metastasis

9 September 2017

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New insights into osteoporosis: the bone-fat connection

9 September 2017

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Macrophage cathepsin K promotes prostate tumor progression in bone

9 September 2017

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Lipids and prostate cancer

9 September 2017

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Marrow fat metabolism is linked to the systemic energy metabolism

9 September 2017

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Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes

9 September 2017

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High‐fat diet activates pro‐inflammatory response in the prostate through association of Stat‐3 and NF‐κB

9 September 2017

1 reference

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Cancer to bone: a fatal attraction

9 September 2017

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β2-Microglobulin Induces Epithelial to Mesenchymal Transition and Confers Cancer Lethality and Bone Metastasis in Human Cancer Cells

9 September 2017

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Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

9 September 2017

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Skeletal aging and the adipocyte program: New insights from an "old" molecule

9 September 2017

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Treatment and prevention of bone complications from prostate cancer

9 September 2017

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Release of inflammatory mediators by human adipose tissue is enhanced in obesity and primarily by the nonfat cells: a review

9 September 2017

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Cellular and molecular mechanisms of bone remodeling.

9 September 2017

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PPARs in bone: the role in bone cell differentiation and regulation of energy metabolism

9 September 2017

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Saturated fatty acids enhance osteoclast survival

9 September 2017

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Interleukin-6 in bone metastasis and cancer progression.

9 September 2017

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High fat diet-induced animal model of age-associated obesity and osteoporosis

9 September 2017

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Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer

9 September 2017

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Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis

9 September 2017

1 reference

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Marrow fat and the bone microenvironment: developmental, functional, and pathological implications

9 September 2017

1 reference

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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance

9 September 2017

1 reference

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Cathepsin K: a therapeutic target for bone diseases

9 September 2017

1 reference

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Molecular mechanisms of metastasis in prostate cancer

9 September 2017

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The interleukin-8 pathway in cancer.

9 September 2017

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Osteoclasts are active in bone forming metastases of prostate cancer patients

9 September 2017

1 reference

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Molecular biology of bone metastasis

9 September 2017

1 reference

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Basic mechanisms responsible for osteolytic and osteoblastic bone metastases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Mechanisms of disease: is osteoporosis the obesity of bone?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Bone and fat: old questions, new insights

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Mechanisms of bone metastasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Metastatic bone disease: clinical features, pathophysiology and treatment strategies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

CXCL5 stimulation of RANK ligand expression in Paget's disease of bone

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and CXCL2 in ovarian and endometrial cancer cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

CXC chemokine ligand 2 induced by receptor activator of NF-kappa B ligand enhances osteoclastogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

DNA microarray analyses of genes expressed differentially in 3T3-L1 adipocytes co-cultured with murine macrophage cell line RAW264.7 in the presence of the toll-like receptor 4 ligand bacterial endotoxin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Receptor activator of NF-kappaB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Bone turnover mediates preferential localization of prostate cancer in the skeleton.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Prostate cancer cell growth is modulated by adipocyte‐cancer cell interaction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Autocrine signaling is a key regulatory element during osteoclastogenesis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

The chemokine Cxcl1 is a novel target gene of parathyroid hormone (PTH)/PTH-related protein in committed osteoblasts

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393805

High bone turnover markers predict poor outcome in patients with bone metastasis

22 August 2018

1 reference

12 December 2020

Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy

1 reference

12 December 2020

Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice

1 reference

12 December 2020

Osteoblast progenitor fate and age-related bone loss

1 reference

12 December 2020

Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption

1 reference

12 December 2020

Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial

1 reference

12 December 2020

Osteoclastogenesis by bone marrow-derived macrophages is enhanced in obese mice

1 reference

12 December 2020

The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies

1 reference

12 December 2020

10.1007/S10585-015-9714-5

Identifiers

DOI

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference

7 September 2017

PubMed publication ID

25802102

1 reference