Insight into rheumatological cause and effect through the use of Mendelian randomization (Q38895577)

7 September 2017

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title

Insight into rheumatological cause and effect through the use of Mendelian randomization. (English)

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7 September 2017

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7 September 2017

Philip C Robinson

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7 September 2017

Hyon K Choi

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7 September 2017

Ron Do

series ordinal

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7 September 2017

language of work or name

English

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publication date

14 July 2016

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Nature Reviews Rheumatology

7 September 2017

published in

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7 September 2017

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7 September 2017

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7 September 2017

page(s)

486-496

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Cigarette smoking and risk of rheumatoid arthritis: a dose-response meta-analysis

7 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Sugar-sweetened beverage consumption: a risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Effects of soft drink consumption on nutrition and health: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and Nutrition Examination Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization studies: a review of the approaches used and the quality of reporting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Reduced glomerular function and prevalence of gout: NHANES 2009-10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Uric acid and incident kidney disease in the community

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Methodological challenges in mendelian randomization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Specification Tests in Econometrics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Avoiding bias from weak instruments in Mendelian randomization studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian Randomization: New Applications in the Coming Age of Hypothesis-Free Causality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Using multiple genetic variants as instrumental variables for modifiable risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

New loci associated with kidney function and chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Twenty-eight loci that influence serum urate levels: analysis of association with gout.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

FGF23 gene variation and its association with phosphate homeostasis and bone mineral density in Finnish children and adolescents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Causal or Noncausal Relationship of Uric Acid With Diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

An update on the genetic architecture of hyperuricemia and gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Loci influencing blood pressure identified using a cardiovascular gene-centric array

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Weight Loss, the Obesity Paradox, and the Risk of Death in Rheumatoid Arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Allopurinol and progression of CKD and cardiovascular events: long-term follow-up of a randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Serum uric acid and cognitive function and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Contribution of uric acid to cancer risk, recurrence, and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Uric acid: the oxidant-antioxidant paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The Role of Uric Acid as an Endogenous Danger Signal in Immunity and Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

A prospective study of gout and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Leukemia, lymphoma, and multiple myeloma following selected medical conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Increased risk of cancer among gout patients: a nationwide population study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Use of Mendelian randomisation to assess potential benefit of clinical intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization: nature's randomized trial in the post-genome era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Lack of gene-diuretic interactions on the risk of incident gout: the Nurses' Health Study and Health Professionals Follow-up Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Apolipoprotein E isoforms, serum cholesterol, and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian randomization analysis with multiple genetic variants using summarized data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Effects of torcetrapib in patients at high risk for coronary events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Effects of dalcetrapib in patients with a recent acute coronary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Homocyst(e)ine and cardiovascular disease: a systematic review of the evidence with special emphasis on case-control studies and nested case-control studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Guidelines for pregnancy: what's an acceptable risk, and how is the evidence (finally) shaping up?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Alcohol consumption and blood pressure in the 1982 Maryland Hypertension Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Alcohol consumption and the incidence of hypertension: The Atherosclerosis Risk in Communities Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Alcohol and blood pressure: the INTERSALT study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Supplementation with cholecalciferol does not result in weight reduction in overweight and obese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Vitamin D3 and the risk of CVD in overweight and obese women: a randomised controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Lipoprotein(a) and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The association between circulating lipoprotein(a) and type 2 diabetes: is it causal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

The role of genetic polymorphisms regulating vitamin D levels in rheumatoid arthritis outcome: a Mendelian randomisation approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Mendelian Randomization and Estimation of Treatment Efficacy for Chronic Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Uric acid and chronic kidney disease: new understanding of an old problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Serum uric acid and cognitive function in community-dwelling older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Raised serum urate concentration as risk factor for premature mortality in middle aged men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Raised serum urate concentration as risk factor for premature mortality in middle aged men: relation to death from cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Low circulating vitamin D in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Meta-analysis of Mendelian randomization studies incorporating all three genotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.102

Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study

31 March 2020

1 reference

12 December 2020

The effects of high phosphorus intake on calcium homeostasis

1 reference

12 December 2020

Serum uric acid unrelated to cancer incidence in humans

1 reference

12 December 2020

Relationship of serum uric acid to cancer occurrence in a prospective male cohort

1 reference

12 December 2020

Uric acid levels in patients with multiple sclerosis: analysis in mono- and dizygotic twins

1 reference

12 December 2020

Risk factors for gout and prevention: a systematic review of the literature

1 reference

12 December 2020

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

1 reference

5 October 2024

https://opencitations.net/index/api/v1/citations/10.1093/HMG/DDT177

Identifiers

DOI

10.1038/NRRHEUM.2016.102

1 reference

Dimensions Publication ID

7 September 2017

1022884098

0 references

1 reference