Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model. (Q38879452)

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scientific article published on 4 May 2015

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English	Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model.	scientific article published on 4 May 2015

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scholarly article

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7 March 2020

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model (English)

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7 March 2020

oncolytic virus

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based on heuristic

inferred from title

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based on heuristic

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pancreatic cancer

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1

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7 March 2020

Carlos Bravo-Perez

7

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7 March 2020

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M Bunuales

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M Gonzalez-Aparicio

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E Garcia-Aragoncillo

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J I Quetglas

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7 March 2020

R Casado

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P Alzuguren

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7 March 2020

R Hernandez-Alcoceba

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7 March 2020

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4 May 2015

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7 March 2020

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7 March 2020

22

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7 March 2020

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7 March 2020

696-706

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7 March 2020

Cytokine gene-mediated immunotherapy: current status and future perspectives

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Going viral with cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Oncolytic viruses for induction of anti-tumor immunity

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

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Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

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Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Interleukin-12: biological properties and clinical application

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

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Collapse of the tumor stroma is triggered by IL-12 induction of Fas.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

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Neoadjuvant treatment of hepatic malignancy: an oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects against recurrence-after resection.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Human adenovirus replicates in immunocompetent models of pancreatic cancer in Syrian hamsters

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Membrane-tethered proteins for basic research, imaging, and therapy.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Cancer immunotherapy using a membrane-bound interleukin-12 with B7-1 transmembrane and cytoplasmic domains.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Cellular cofactors affecting hepatitis C virus infection and replication

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

miR-122a-Regulated Expression of a Suicide Gene Prevents Hepatotoxicity Without Altering Antitumor Effects in Suicide Gene Therapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Functional analysis of the transmembrane (TM) domain of the Autographa californica multicapsid nucleopolyhedrovirus GP64 protein: substitution of heterologous TM domains

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

The HaP-T1 Syrian golden hamster pancreatic cancer model: cell implantation is better than tissue implantation

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Immunosuppression enhances oncolytic adenovirus replication and antitumor efficacy in the Syrian hamster model.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Synergistic anti-tumor effect of glycosylphosphatidylinositol-anchored IL-2 and IL-12.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Low-dose adenoviral immunotherapy of rat hepatocellular carcinoma using single-chain interleukin-12.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Transient depletion of specific immune cell populations to improve adenovirus-mediated transgene expression in the liver

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Self-inactivating helper virus for the production of high-capacity adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Real-time quantification of microRNAs by stem-loop RT-PCR

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2015.45

21 January 2018

Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/25938192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycolipid-anchored IL-12 expressed on tumor cell surface induces antitumor immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/25938192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPI-anchoring of GM-CSF results in active membrane-bound and partially shed cytokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25938192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25938192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25938192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/GT.2015.45

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25938192%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25938192%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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