Optimizing T-cell receptor gene therapy for hematologic malignancies. (Q38840466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

review article

1 reference

title

Optimizing T-cell receptor gene therapy for hematologic malignancies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Hans J Stauss

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

20 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

number of pages

1 reference

inferred from page(s)

published in

Blood

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

127

1 reference

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2 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

3305-3311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

T-cell receptor gene therapy--ready to go viral?

2 April 2020

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1 reference

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High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

9 September 2017

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9 September 2017

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9 September 2017

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Tumor-associated macrophages: from mechanisms to therapy

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Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.

9 September 2017

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Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma

9 September 2017

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Adoptive immunotherapy for cancer or viruses

9 September 2017

1 reference

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Signatures of mutational processes in human cancer

9 September 2017

1 reference

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Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells

9 September 2017

1 reference

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Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection

9 September 2017

1 reference

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Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

9 September 2017

1 reference

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

9 September 2017

1 reference

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Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

9 September 2017

1 reference

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Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

9 September 2017

1 reference

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Peptidases trimming MHC class I ligands

9 September 2017

1 reference

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Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

9 September 2017

1 reference

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

9 September 2017

1 reference

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

9 September 2017

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Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanoma

9 September 2017

1 reference

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Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies.

9 September 2017

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Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

9 September 2017

1 reference

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An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data

9 September 2017

1 reference

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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

9 September 2017

1 reference

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Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma

9 September 2017

1 reference

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Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells

9 September 2017

1 reference

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Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

9 September 2017

1 reference

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Facilitating matched pairing and expression of TCR chains introduced into human T cells

9 September 2017

1 reference

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Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

9 September 2017

1 reference

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Cancer regression in patients after transfer of genetically engineered lymphocytes

9 September 2017

1 reference

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A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

9 September 2017

1 reference

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BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical correlations

9 September 2017

1 reference

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

9 September 2017

1 reference

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Selectivity of MHC-encoded peptide transporters from human, mouse and rat

9 September 2017

1 reference

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Structure of the human class I histocompatibility antigen, HLA-A2

9 September 2017

1 reference

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The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

9 September 2017

1 reference

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Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

9 September 2017

1 reference

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Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

9 September 2017

1 reference

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Two overlapping subdominant epitopes identified by DNA immunization induce protective CD8(+) T-cell populations with differing cytolytic activities

14 September 2017

1 reference

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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

14 September 2017

1 reference

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Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

14 September 2017

1 reference

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Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

14 September 2017

1 reference

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Generation of human tumor-reactive cytotoxic T cells against peptides presented by non-self HLA class I molecules

25 September 2017

1 reference

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Serial triggering of many T-cell receptors by a few peptide-MHC complexes

25 September 2017

1 reference

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Optimization of the HA-1-specific T-cell receptor for gene therapy of hematologic malignancies

25 September 2017

1 reference

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Cellular peptide composition governed by major histocompatibility complex class I molecules.

17 June 2018

1 reference

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

17 June 2018

1 reference

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B cells turn off virgin but not memory T cells

17 June 2018

1 reference

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HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.

17 June 2018

1 reference

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Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

HLA class II upregulation during viral infection leads to HLA-DP-directed graft-versus-host disease after CD4+ donor lymphocyte infusion.

22 August 2018

1 reference

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Human MHC Class I-restricted high avidity CD4+ T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

CD3 limits the efficacy of TCR gene therapy in vivo

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells

22 August 2018

1 reference

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Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes

22 August 2018

1 reference

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Identification of two cytotoxic T lymphocyte-recognized epitopes in the Ras protein

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316910

Abrogation of CTL Epitope Processing by Single Amino Acid Substitution Flanking the C-Terminal Proteasome Cleavage Site

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27207802

12 December 2020

inferred from PubMed ID database lookup

Proteosomal degradation of BCR/ABL protein can generate an HLA-A*0301-restricted peptide, but high-avidity T cells recognizing this leukemia-specific antigen were not demonstrated

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27207802

12 December 2020

inferred from PubMed ID database lookup

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27207802

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2015-11-629071

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

PubMed publication ID

27207802

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207802%20AND%20SRC:MED&resulttype=core&format=json