Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model (Q38839414)

14 July 2018

title

Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model (English)

1 reference

14 July 2018

1 reference

Li-Rong Shao

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14 July 2018

Carl E Stafstrom

series ordinal

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14 July 2018

language of work or name

English

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publication date

12 April 2017

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14 July 2018

Journal of Neurophysiology

published in

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14 July 2018

volume

118

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14 July 2018

issue

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14 July 2018

page(s)

103-113

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14 July 2018

Metabolic Therapy for Temporal Lobe Epilepsy in a Dish: Investigating Mechanisms of Ketogenic Diet using Electrophysiological Recordings in Hippocampal Slices

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2-Deoxy-d-Glucose (2-DG)-Induced Cardiac Toxicity in Rat: NT-proBNP and BNP as Potential Early Cardiac Safety Biomarkers

15 July 2018

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Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

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Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy

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Oxygen and seizure dynamics: II. Computational modeling

15 July 2018

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Oxygen and seizure dynamics: I. Experiments

15 July 2018

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Ketogenic diet for adults in super-refractory status epilepticus

15 July 2018

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The ketogenic diet: metabolic influences on brain excitability and epilepsy

15 July 2018

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Enhanced glutamate uptake into synaptic vesicles fueled by vesicle-generated ATP from phosphoenolpyruvate and ADP. Proposed role of a novel enzyme

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The ketogenic diet as a treatment paradigm for diverse neurological disorders

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Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation

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Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats

15 July 2018

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Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models

15 July 2018

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Are purines mediators of the anticonvulsant/neuroprotective effects of ketogenic diets?

15 July 2018

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Electrogenic Na+/Ca2+-exchange of nerve and muscle cells

15 July 2018

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Cellular pathways of energy metabolism in the brain: is glucose used by neurons or astrocytes?

15 July 2018

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2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure

15 July 2018

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Brain work and brain imaging

15 July 2018

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Energy metabolism in the brain

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Correlating structure and function in ATP-sensitive K+ channels.

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes.

15 July 2018

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Excitatory synaptic interactions between CA3 neurones in the guinea-pig hippocampus

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Glucose concentration inversely alters neocortical slice excitability through an osmotic effect

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Osmotic effects on the CA1 neuronal population in hippocampal slices with special reference to glucose

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Participation of calcium spikes during intrinsic burst firing in hippocampal neurons

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

2-Deoxy-d-glucose enhances tonic inhibition through the neurosteroid-mediated activation of extrasynaptic GABAA receptors.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Behavioral, cognitive, and safety profile of 2-deoxy-2-glucose (2DG) in adult rats

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Both synaptic and intrinsic mechanisms underlie the different properties of population bursts in the hippocampal CA3 area of immature versus adult rats

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Efficacy and connectivity of intracolumnar pairs of layer 2/3 pyramidal cells in the barrel cortex of juvenile rats

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Intrinsic bursting of immature CA3 pyramidal neurons and consequent giant depolarizing potentials are driven by a persistent Na+ current and terminated by a slow Ca2+ -activated K+ current

22 August 2018

1 reference

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Hypoosmolar conditions reduce extracellular volume fraction and enhance epileptiform activity in the CA3 region of the immature rat hippocampus

22 August 2018

1 reference

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The molecular machinery of Keilin's respiratory chain

22 August 2018

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Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase

22 August 2018

1 reference

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The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers.

22 August 2018

1 reference

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Epileptiform discharge induced by 4-aminopyridine in magnesium-free medium in neocortical neurons: physiological and pharmacological characterization

22 August 2018

1 reference

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Cellular mechanism of neuronal synchronization in epilepsy

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5494374

Endogenous nature of spontaneous bursting in hippocampal pyramidal neurons

22 August 2018

1 reference

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The possible role of endogenous glutathione as an anticonvulsant in mice

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28404824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Penicillin-induced epileptogenesis in immature rat CA3 hippocampal pyramidal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28404824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ketogenic diet: a time-tested, effective, and safe method for treatment of intractable childhood epilepsy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28404824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/JN.00100.2017

1 reference

14 July 2018

PMC publication ID

5494374

1 reference

14 July 2018

PubMed publication ID

28404824

1 reference

14 July 2018