MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling (Q38821957)

4 March 2018

title

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling (English)

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4 March 2018

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4 March 2018

Rudolf Jaenisch

object named as

R Jaenisch

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4 March 2018

N Mellios

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4 March 2018

D A Feldman

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4 March 2018

S D Sheridan

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J P K Ip

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S Kwok

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4 March 2018

S K Amoah

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B Rosen

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B A Rodriguez

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B Crawford

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R Swaminathan

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S Chou

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M Ziats

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C Ernst

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S J Haggarty

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M Sur

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4 March 2018

language of work or name

English

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publication date

25 April 2017

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4 March 2018

published in

Molecular Psychiatry

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4 March 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5815944/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.

17 June 2018

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Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males

17 June 2018

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Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy

17 June 2018

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Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex

17 June 2018

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MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

17 June 2018

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Rett syndrome: a prototypical neurodevelopmental disorder

17 June 2018

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Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Survey of MeCP2 in the Rett syndrome and the non-Rett syndrome brain

17 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

The phenotypic consequences of MECP2 mutations extend beyond Rett syndrome

17 June 2018

1 reference

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Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Rett syndrome neuropathology review 2000.

17 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

MECP2 mutations in sporadic cases of Rett syndrome are almost exclusively of paternal origin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Selective dendritic alterations in the cortex of Rett syndrome

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Early clinical signs in the Rett disorder

17 June 2018

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miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Disrupted ERK signaling during cortical development leads to abnormal progenitor proliferation, neuronal and network excitability and behavior, modeling human neuro-cardio-facial-cutaneous and related syndromes

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Increased MECP2 gene copy number as the result of genomic duplication in neurodevelopmentally delayed males.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression

22 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Delayed maturation of neuronal architecture and synaptogenesis in cerebral cortex of Mecp2-deficient mice

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Is the early development of girls with Rett disorder really normal?

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex

22 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5815944

Neonatal encephalopathy in two boys in families with recurrent Rett syndrome

22 August 2018

1 reference

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An increase in MECP2 dosage impairs neural tube formation

22 August 2018

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Transcriptome analysis by strand-specific sequencing of complementary DNA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2017.86

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.86

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MP.2017.86

1 reference

4 March 2018

PMC publication ID

5815944

1 reference

4 March 2018

PubMed publication ID

28439102

1 reference

4 March 2018