Valproic acid inhibits the angiogenic potential of cervical cancer cells via HIF-1α/VEGF signals (Q38788965)

6 September 2017

title

Valproic acid inhibits the angiogenic potential of cervical cancer cells via HIF-1α/VEGF signals (English)

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6 September 2017

main subject

cervix uterine cancer

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Y Zhao

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6 September 2017

W You

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6 September 2017

J Zheng

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6 September 2017

Y Chi

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6 September 2017

W Tang

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6 September 2017

R Du

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6 September 2017

publication date

4 March 2016

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Clinical and Translational Oncology

6 September 2017

published in

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6 September 2017

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6 September 2017

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6 September 2017

page(s)

1123-1130

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Worldwide burden of cervical cancer in 2008.

6 September 2017

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Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action

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Valproic acid inhibits the growth of cervical cancer both in vitro and in vivo

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Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathways.

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Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines

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Valproic acid decreases urothelial cancer cell proliferation and induces thrombospondin-1 expression

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Valproic acid inhibits angiogenesis in vitro and in vivo

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Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid.

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Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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Valproic acid treatment inhibits hypoxia-inducible factor 1α accumulation and protects against burn-induced gut barrier dysfunction in a rodent model

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Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome

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12 December 2020

Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors

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12 December 2020

Inhibitory effect of valproic acid on bladder cancer in combination with chemotherapeutic agents in vitro and in vivo

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12 December 2020

Effects of valproic acid on proliferation, apoptosis, angiogenesis and metastasis of ovarian cancer in vitro and in vivo

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12 December 2020

Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway

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12 December 2020

Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylation

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12 December 2020

Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi‑1 leukemia cells

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12 December 2020

A comparison of radical vaginal hysterectomy combined with extraperitoneal or laparoscopic pelvic lymphadenectomy in the treatment of cervical cancer

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12 December 2020

10.1007/S12094-016-1494-0

Identifiers

DOI

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6 September 2017

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