miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose (Q38784593)

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scientific article published on 21 February 2016

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English	miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose	scientific article published on 21 February 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose (English)

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

0 references

0 references

toll-like receptor

0 references

author name string

Eun-Ah Ye

1

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Jena J Steinle

2

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

publication date

21 February 2016

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Mediators of Inflammation

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Europe PubMed Central

PMC publication ID

6 September 2017

2016

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

3958453

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

copyright license

Creative Commons Attribution 4.0 International

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

HMGB1 is activated in type 2 diabetes mellitus patients and in mesangial cells in response to high glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Hyperglycemia induces Toll-like receptor-2 and -4 expression and activity in human microvascular retinal endothelial cells: implications for diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Epigenetic mechanisms in diabetic complications and metabolic memory

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6 September 2017

The role of TLR2 and 4-mediated inflammatory pathways in endothelial cells exposed to high glucose

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Up-regulation of miR-146a contributes to the inhibition of invasion of pancreatic cancer cells

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6 September 2017

Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury

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The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer

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Sirt1, a negative regulator of matrix metalloproteinase-9 in diabetic retinopathy

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6 September 2017

Regulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina

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6 September 2017

MitomiRs in human inflamm-aging: a hypothesis involving miR-181a, miR-34a and miR-146a

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6 September 2017

High-mobility group box-1 and its role in angiogenesis

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MicroRNA-196a is a putative diagnostic biomarker and therapeutic target for laryngeal cancer.

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6 September 2017

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

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Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice

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6 September 2017

Reduced insulin receptor signaling in retinal Müller cells cultured in high glucose

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6 September 2017

Insulin-like growth factor binding protein-3 inhibits monocyte adhesion to retinal endothelial cells in high glucose conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1β, tumor necrosis factor-α, and interferon-γ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

TXNIP links innate host defense mechanisms to oxidative stress and inflammation in retinal Muller glia under chronic hyperglycemia: implications for diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

miR-146a-Mediated extracellular matrix protein production in chronic diabetes complications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling

1 reference

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6 September 2017

Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cells

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New Advances in RNAs

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6 September 2017

Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells

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6 September 2017

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1).

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6 September 2017

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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6 September 2017

Hyperglycemia increases mitochondrial superoxide in retina and retinal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

6 September 2017

miR-195 regulates SIRT1-mediated changes in diabetic retinopathy.

1 reference

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miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease

1 reference

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6 September 2017

MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats

1 reference

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14 September 2017

miR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

25 September 2017

Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

25 September 2017

MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

25 September 2017

TNFα and SOCS3 regulate IRS-1 to increase retinal endothelial cell apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

25 September 2017

Cellular mechanisms of high mobility group 1 (HMGB-1) protein action in the diabetic retinopathy.

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23 June 2018

Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells.

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31 August 2018

Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats

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31 August 2018

Mechanisms of endothelial to mesenchymal transition in the retina in diabetes

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31 August 2018

MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

31 August 2018

Heme oxygenase-2 suppress TNF-α and IL6 expression via TLR4/MyD88-dependent signaling pathway in mouse cerebral vascular endothelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

31 August 2018

Involvement of HMGB1 mediated signalling pathway in diabetic retinopathy: evidence from type 2 diabetic rats and ARPE-19 cells under diabetic condition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

31 August 2018

Effect of TRIF on permeability and apoptosis in bovine microvascular endothelial cells exposed to lipopolysaccharide

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31 August 2018

Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes.

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31 August 2018

Early release of HMGB-1 from neurons after the onset of brain ischemia

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31 August 2018

Small molecular weight G-protein, H-Ras, and retinal endothelial cell apoptosis in diabetes

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31 August 2018

Interactions between hyperglycemia and hypoxia: implications for diabetic retinopathy

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31 August 2018

Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants.

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31 August 2018

Relationship of hyperglycemia to the long-term incidence and progression of diabetic retinopathy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4779539

31 August 2018

Hyperglycemia as a cause of diabetic retinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26997759

12 December 2020

based on heuristic

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Differential microRNA (miRNA) expression could explain microbial tolerance in a novel chronic peritonitis model

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https://pubmed.ncbi.nlm.nih.gov/26997759

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inferred from PubMed ID database lookup

Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/26997759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tacrolimus (FK506) prevents early retinal neovascularization in streptozotocin-induced diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/26997759

12 December 2020

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1 reference

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10.1155/2016/3958453

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Europe PubMed Central

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6 September 2017

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24 November 2022

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Europe PubMed Central

PMC publication ID

6 September 2017

PubMed publication ID

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Europe PubMed Central

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6 September 2017

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