Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives. (Q38712547)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28285912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives (English)

1 reference

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5 April 2020

Gao-Xiang Zhu

1 reference

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5 April 2020

Pi-Le Cheng

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5 April 2020

Masuo Goto

1 reference

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5 April 2020

Na Zhang

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5 April 2020

Susan L Morris-Natschke

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5 April 2020

Guan-Zhou Yang

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5 April 2020

Qian-Ru Yang

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5 April 2020

Ying-Qian Liu

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5 April 2020

Hai-Le Chen

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5 April 2020

Xiao-Shuai Zhang

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5 April 2020

language of work or name

English

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publication date

28 February 2017

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Bioorganic & Medicinal Chemistry Letters

5 April 2020

published in

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5 April 2020

volume

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5 April 2020

issue

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5 April 2020

page(s)

1750-1753

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Piperazine scaffold: A remarkable tool in generation of diverse pharmacological agents

5 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Perspectives on biologically active camptothecin derivatives

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Design and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogs

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents

23 June 2018

1 reference

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Synthesis of new camptothecin analogs with improved antitumor activities

23 June 2018

1 reference

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Network pharmacology: the next paradigm in drug discovery

23 June 2018

1 reference

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Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

23 June 2018

1 reference

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Synthesis and cytotoxic activity of polyamine analogues of camptothecin

23 June 2018

1 reference

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Review camptothecin: current perspectives

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Camptothecin: current perspectives

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Sulfonamides and sulfonylated derivatives as anticancer agents

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Novel 7-substituted camptothecins with potent antitumor activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

New colorimetric cytotoxicity assay for anticancer-drug screening

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Chemical Modification of an Antitumor Alkaloid Camptothecin: Synthesis and Antitumor Activity of 7-C-Substituted Camptothecins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

New analogues of camptothecins. Activity and resistance.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5512430

Alkyl Esters of Camptothecin and 9-Nitrocamptothecin: Synthesis, in Vitro Pharmacokinetics, Toxicity, and Antitumor Activity

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28285912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemistry of the camptothecins in the bloodstream. Drug stabilization and optimization of activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28285912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2017.02.066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28285912%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

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5 April 2020

PubMed publication ID

28285912

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28285912%20AND%20SRC:MED&resulttype=core&format=json