Gentamicin nephrotoxicity in animals: Current knowledge and future perspectives (Q38683479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507482%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

review article

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title

Gentamicin nephrotoxicity in animals: Current knowledge and future perspectives (English)

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20 March 2020

0 references

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20 March 2020

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20 March 2020

Slavimir Veljkovic

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20 March 2020

Nenad Stojiljkovic

series ordinal

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20 March 2020

Ivan Ilic

series ordinal

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20 March 2020

publication date

24 March 2017

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20 March 2020

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20 March 2020

volume

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20 March 2020

page(s)

388-399

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Nitric oxide and oxidative stress in vascular disease

20 March 2020

cites work

1 reference

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Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney

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Tubuloglomerular feedback mechanisms in nephron segments beyond the macula densa

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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A novel method for the evaluation of proximal tubule epithelial cellular necrosis in the intact rat kidney using ethidium homodimer

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Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis.

6 September 2017

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Gentamicin binds to the lectin site of calreticulin and inhibits its chaperone activity

6 September 2017

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S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo

6 September 2017

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Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity

6 September 2017

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Acute renal failure: is nitric oxide the bad guy?

6 September 2017

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Apoptotic pathways of oxidative damage to renal tubular epithelial cells

6 September 2017

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Nitric oxide and apoptosis in mesangial cells

6 September 2017

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The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm

6 September 2017

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Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides

6 September 2017

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Increased renal glomerular endothelin-1 release in gentamicin-induced nephrotoxicity

6 September 2017

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Acute gentamicin‐induced hypercalciuria and hypermagnesiuria in the rat: dose‐response relationship and role of renal tubular injury

6 September 2017

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Gentamicin nephrotoxicity in humans and animals: some recent research

6 September 2017

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Molecular parameters involved in aminoglycoside nephrotoxicity

6 September 2017

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Nephrotoxicity of immunosuppressive drugs.

6 September 2017

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Mechanisms of aminoglycoside nephrotoxicity

6 September 2017

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Aminoglycoside-induced renal phospholipidosis and nephrotoxicity

6 September 2017

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Subcellular distribution of gentamicin in proximal tubular cells, determined by immunogold labeling

6 September 2017

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Drug-phospholipid interactions: role in aminoglycoside nephrotoxicity

6 September 2017

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14 September 2017

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14 September 2017

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Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury

25 September 2017

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Gentamicin inhibits agonist stimulation of the phosphatidylinositol cascade in primary cultures of rabbit proximal tubular cells and in rat renal cortex

25 September 2017

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25 September 2017

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Involvement of phospholipase A2 in gentamicin-induced rat mesangial cell activation

23 June 2018

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Mechanisms for protective effects of free radical scavengers on gentamicin-mediated nephropathy in rats

23 June 2018

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Mechanism of gentamicin nephrotoxicity in rats and the protective effect of zinc-induced metallothionein synthesis.

23 June 2018

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Effect of netilmicin and amikacin on urinary phospholipids excretion in humans.

23 June 2018

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A light and electron microscopic analysis of gentamicin nephrotoxicity in rats

23 June 2018

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23 June 2018

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Beneficial effects of calcium oral coadministration in gentamicin-induced nephrotoxicity in rats.

23 June 2018

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Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

31 August 2018

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31 August 2018

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Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein.

31 August 2018

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Glomerular basement membrane alterations induced by gentamicin administration in rats

31 August 2018

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Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys.

31 August 2018

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Resveratrol inhibits gentamicin-induced mesangial cell contraction

31 August 2018

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Gentamicin induces Jun-AP1 expression and JNK activation in renal glomeruli and cultured mesangial cells

31 August 2018

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Temporal adaptation of tubuloglomerular feedback: effects of COX-2.

31 August 2018

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Altered NMDA receptor expression in renal toxicity: Protection with a receptor antagonist

31 August 2018

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Gentamicin treatment induces simultaneous mesangial proliferation and apoptosis in rats

31 August 2018

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Effect of tempol (4-hydroxy tempo) on gentamicin-induced nephrotoxicity in rats

31 August 2018

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Aminoglycosides suppress tRNA processing in human epidermal keratinocytes in vitro

31 August 2018

1 reference

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Protective effect of trans-resveratrol on gentamicin-induced nephrotoxicity

31 August 2018

1 reference

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Involvement of reactive oxygen species on gentamicin-induced mesangial cell activation.

31 August 2018

1 reference

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A role for superoxide in gentamicin-mediated nephropathy in rats

31 August 2018

1 reference

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TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers

31 August 2018

1 reference

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Protective effects of vitamin e and probucol against gentamicin-induced nephrotoxicity in rats

31 August 2018

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How Cytotoxic is Nitric Oxide?

31 August 2018

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Effect of gentamicin treatment on glutamine and lactate metabolism by the renal cortex of the rat.

31 August 2018

1 reference

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Salicylic acid attenuates gentamicin-induced nephrotoxicity in rats

31 August 2018

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The pathology of acute renal failure due to interstitial nephritis in man with comments on the role of interstitial inflammation and sex in gentamicin nephrotoxicity

3 December 2018

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12 December 2020

Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid

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12 December 2020

Early effects of gentamicin, tobramycin, and amikacin on the human kidney

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12 December 2020

Protective effect of L-arginine intake on the impaired renal vascular responses in the gentamicin-treated rats

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12 December 2020

Up-regulation of Bcl-2 by redox signals in glomerular mesangial cells

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12 December 2020

Tubular injury and regeneration in the rat kidney following acute exposure to gentamicin: a time-course study

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12 December 2020

Tetramethylpyrazine protects rat renal tubular cell apoptosis induced by gentamicin

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12 December 2020

Glomerular permeability to macromolecules in gentamicin-treated rats

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12 December 2020

Gentamicin activates rat mesangial cells. A role for platelet activating factor

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12 December 2020

Phospholipase A2 in mesangial cells: control mechanisms and functional importance

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12 December 2020

Once-daily dosing decreases renal accumulation of gentamicin and netilmicin

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12 December 2020

Nephrotoxic effects of aminoglycoside treatment on renal protein reabsorption and accumulation

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12 December 2020

Evolution of morphologic changes after intravitreous injection of gentamicin

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12 December 2020

Dysregulation of renal sodium transporters in gentamicin-treated rats

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12 December 2020

Involvement of platelet-activating factor in gentamicin nephrotoxicity in rats

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12 December 2020

Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells

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12 December 2020

Proteases in renal cell death: calpains mediate cell death produced by diverse toxicants

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12 December 2020

Role of calcium in gentamicin-induced mesangial cell activation

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12 December 2020

Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin

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12 December 2020

Protective effect of selenium on gentamicin-induced oxidative stress and nephrotoxicity in rats

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12 December 2020

Nitric oxide is involved in apoptosis induced by thapsigargin in rat mesangial cells

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12 December 2020

Effect of gentamicin on the lysosomal system of cultured human proximal tubular cells. Endocytotic activity, lysosomal pH and membrane fragility

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12 December 2020

Effects of reactive oxygen species on cultured rat mesangial cells and isolated rat glomeruli

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12 December 2020

Plasma lipid profile in rats with gentamicin-induced nephrotoxicity

1 reference

12 December 2020

Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics

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12 December 2020

Gentamicin treatment increases mesangial cell nitric oxide production

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12 December 2020

Identifiers

DOI

10.17179/EXCLI2017-165

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507482%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507482%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

28507482

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507482%20AND%20SRC:MED&resulttype=core&format=json