Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR). (Q38362637)

2 September 2017

title

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR). (English)

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2 September 2017

Wu S

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2 September 2017

Kaufman RJ

series ordinal

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2 September 2017

language of work or name

English

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publication date

1 January 1996

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

271

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2 September 2017

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2 September 2017

page(s)

1756-1763

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Translational control in mammalian cells

2 September 2017

cites work

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Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

21 January 2018

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Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

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Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members

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A conserved double-stranded RNA-binding domain

21 January 2018

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Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

21 January 2018

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Binding properties of newly identified Xenopus proteins containing dsRNA-binding motifs

21 January 2018

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Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity

21 January 2018

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Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase DAI

21 January 2018

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Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

21 January 2018

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21 January 2018

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Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

21 January 2018

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Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

21 January 2018

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Reversal of the double-stranded-RNA-induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR.

21 January 2018

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Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cells

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The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

21 January 2018

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TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

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Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

21 January 2018

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Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

21 January 2018

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Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domain

21 January 2018

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Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

21 January 2018

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Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

21 January 2018

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The Interferon-Induced Double-Stranded RNA-Activated Human p68 Protein Kinase Potently Inhibits Protein Synthesis in Cultured Cells

21 January 2018

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Vectors used for expression in mammalian cells

21 January 2018

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Transcriptional control in the production of liver-specific mRNAs

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.3.1756

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2 September 2017

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