Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions (Q38353402)

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English	Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions (English)

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

single-nucleotide polymorphism

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

Jordi Pérez-Tur

6

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

John Anthony Hardy

4

object named as

John Hardy

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Europe PubMed Central

PMC publication ID

15 June 2018

Ronald C. Petersen

3

object named as

Ronald C Petersen

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Europe PubMed Central

PMC publication ID

15 June 2018

author name string

Yuan-Wen Ge

2

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

Jack T Rogers

5

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

Debomoy K Lahiri

7

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

publication date

1 January 2010

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

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Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

153B

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

1

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

185-201

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice

1 reference

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Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.

1 reference

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Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease.

1 reference

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SP1 transcription factors in male germ cell development and differentiation

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How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD.

1 reference

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

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Cholesterol, APOE genotype, and Alzheimer disease: an epidemiologic study of Nigerian Yoruba

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Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease

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Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?

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Neuronal specific regulatory elements in apolipoprotein E gene proximal promoter.

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LMO3 interacts with neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma

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NF-(kappa)B mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells

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Functional characterization of amyloid beta precursor protein regulatory elements: rationale for the identification of genetic polymorphism

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Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region

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Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors.

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Apolipoprotein E as a target for developing new therapeutics for Alzheimer's disease based on studies from protein, RNA, and regulatory region of the gene

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Alzheimer Disease in the US Population

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ApoE genotype, past adult lead exposure, and neurobehavioral function

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Sp1 and AP2 transcription factors are required for the human fragile mental retardation promoter activity in SK-N-SH neuronal cells

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Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene.

1 reference

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Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease

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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

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APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population.

1 reference

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A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

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Haplogroup analysis of the risk associated with APOE promoter polymorphisms (-219T/G, -491A/T and -427T/C) in Colombian Alzheimer's disease patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19504470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in NF-kappaB, AP-1 and SP-1 activities in neuronal cells expressing presenilin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19504470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-day apolipoprotein E genotyping

1 reference

https://pubmed.ncbi.nlm.nih.gov/19504470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/19504470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Th1/E47cs-G apolipoprotein E (APOE) promoter allele is a risk factor for Alzheimer disease of very later onset

1 reference

https://pubmed.ncbi.nlm.nih.gov/19504470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/AJMG.B.30973

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 June 2018

http://europepmc.org/abstract/PMC/5875733

ResearchGate publication ID

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