Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion. (Q38356421)

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English	Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.	scientific article

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1 November 2019

Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion (English)

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1 November 2019

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G. Marius Clore

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1 November 2019

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John M Louis

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1 November 2019

Issa Nesheiwat

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1 November 2019

LengChee Chang

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1 November 2019

Carole A Bewley

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24 March 2003

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1 November 2019

Journal of Biological Chemistry

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1 November 2019

278

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1 November 2019

22

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1 November 2019

20278-20285

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1 November 2019

The Role of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in Virus Infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Co-receptors for HIV-1 entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Mechanisms of viral membrane fusion and its inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Core structure of gp41 from the HIV envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Atomic structure of the ectodomain from HIV-1 gp41

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Atomic structure of a thermostable subdomain of HIV-1 gp41

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Capture of an early fusion-active conformation of HIV-1 gp41

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

HIV entry and its inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Design and properties of N(CCG)-gp41, a chimeric gp41 molecule with nanomolar HIV fusion inhibitory activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Protein design of an HIV-1 entry inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Antiviral activity of the neutralizing antibodies 2F5 and 2G12 in asymptomatic HIV-1-infected humans: a phase I evaluation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Quantitative analysis of protein far UV circular dichroism spectra by neural networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeficiency virus type 1 tropism for CD4+ T-cell lines vs. primary macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Fractionation and Characterization of Polyclonal Antibodies Using Three Progressively More Chaotropic Solvents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

2 Production of antisera with small doses of immunogen: multiple intradermal injections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

A mechanism of resistance to HIV-1 entry: inefficient interactions of CXCR4 with CD4 and gp120 in macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301627200

21 January 2018

Identifiers

10.1074/JBC.M301627200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12654905%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12654905%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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