Chemistry and biology of tubulysins: antimitotic tetrapeptides with activity against drug resistant cancers (Q38354179)

2 September 2017

title

Chemistry and biology of tubulysins: antimitotic tetrapeptides with activity against drug resistant cancers (English)

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2 September 2017

Bryan C Murray

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2 September 2017

Michael T Peterson

series ordinal

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2 September 2017

Robert A Fecik

series ordinal

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2 September 2017

language of work or name

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1 May 2015

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2 September 2017

published in

Natural Product Reports

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

654-662

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Discovery of 23 natural tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004.

2 September 2017

cites work

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Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity.

21 January 2018

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Heterologous expression and genetic engineering of the tubulysin biosynthetic gene cluster using Red/ET recombineering and inactivation mutagenesis

21 January 2018

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Multienzyme docking in hybrid megasynthetases

21 January 2018

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Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues

21 January 2018

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Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product

21 January 2018

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Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.

21 January 2018

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Polymeric tubulysin-peptide nanoparticles with potent antitumor activity

21 January 2018

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In vivo structural activity and optimization studies of folate-tubulysin conjugates

21 January 2018

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https://api.crossref.org/works/10.1039%2FC4NP00036F

Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue

21 January 2018

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Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice

21 January 2018

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Cytotoxic simplified tubulysin analogues

21 January 2018

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Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives

21 January 2018

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Structure-activity and high-content imaging analyses of novel tubulysins

21 January 2018

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Design, synthesis, and biological properties of highly potent tubulysin D analogues

21 January 2018

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Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy

21 January 2018

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The multiple multicomponent approach to natural product mimics: tubugis, N-substituted anticancer peptides with picomolar activity.

21 January 2018

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Total syntheses of tubulysins.

21 January 2018

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Synthesis and biological evaluation of tubulysin D analogs related to stereoisomers of tubuvaline

21 January 2018

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Synthesis and structure-activity relationship studies of novel tubulysin U analogues--effect on cytotoxicity of structural variations in the tubuvaline fragment.

21 January 2018

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First total synthesis of tubulysin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00036F

Total synthesis of tubulysin U and its C-4 epimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00036F

The total synthesis of tubulysin D.

21 January 2018

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Toward tubulysin: gram-scale synthesis of tubuvaline-tubuphenylalanine fragment

21 January 2018

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Expedient synthesis of N-methyl tubulysin analogues with high cytotoxicity

21 January 2018

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Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part II: Folic acid conjugates of tubulysins and their hydrazides

21 January 2018

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Synthesis and biological analysis of prostate-specific membrane antigen-targeted anticancer prodrugs

21 January 2018

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Synthesis of linear, beta-cyclodextrin-based polymers and their camptothecin conjugates

21 January 2018

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Antitumor activity of beta-cyclodextrin polymer-camptothecin conjugates

21 January 2018

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Dendrimers as carriers for delivery of chemotherapeutic agents

21 January 2018

1 reference

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Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from Myxobacteria

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.200460147

Tubulysins, new cytostatic peptides from myxobacteria acting on microtubuli. Production, isolation, physico-chemical and biological properties

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.53.879

Identifiers

DOI

10.1039/C4NP00036F

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2 September 2017

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