The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor (Q38328680)

2 September 2017

title

The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor (English)

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2 September 2017

Monzy Thomas

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2 September 2017

Zhigang Yu

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2 September 2017

Nahid Dadgar

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2 September 2017

Sooryanarayana Varambally

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2 September 2017

Jianjun Yu

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2 September 2017

Arul M Chinnaiyan

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2 September 2017

Andrew P Lieberman

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2 September 2017

language of work or name

English

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publication date

30 March 2005

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

280

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2 September 2017

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2 September 2017

page(s)

21264-21271

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Glutamine repeats and neurodegeneration

2 September 2017

cites work

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Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts

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Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

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Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

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IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

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Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

21 January 2018

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

21 January 2018

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The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

21 January 2018

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'Unfolding' pathways in neurodegenerative disease

21 January 2018

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Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M500144200

1 reference

release_xz53fcd5anhw7lbfcf5qjdue5y

2 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xz53fcd5anhw7lbfcf5qjdue5y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference