Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity (Q38317356)

2 September 2017

title

Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity (English)

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2 September 2017

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Marc Halushka

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2 September 2017

Majd AlGhatrif

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2 September 2017

Vabren L Watts

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2 September 2017

Xiaolin Niu

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2 September 2017

Karen L Miller

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2 September 2017

Konrad Vandegaer

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2 September 2017

Djahida Bedja

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2 September 2017

Karen Fox-Talbot

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2 September 2017

Alicja Bielawska

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2 September 2017

Kathleen L Gabrielson

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2 September 2017

Lili A Barouch

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2 September 2017

language of work or name

English

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publication date

2 March 2013

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Journal of Cardiovascular Translational Research

2 September 2017

published in

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

436-445

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Impact of obesity on total and cardiovascular mortality—fat or fiction?

2 September 2017

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Sleep modulates hypertension in leptin-deficient obese mice

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Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

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Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome

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A novel mouse model of lipotoxic cardiomyopathy

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Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

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Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

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Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774.2 macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis

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Ceramide activates a mitochondrial p38 mitogen-activated protein kinase: a potential mechanism for loss of mitochondrial transmembrane potential and apoptosis

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Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

21 January 2018

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Triglyceride accumulation protects against fatty acid-induced lipotoxicity

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Caloric restriction: powerful protection for the aging heart and vasculature.

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Impact of long-term caloric restriction on cardiac senescence: caloric restriction ameliorates cardiac diastolic dysfunction associated with aging.

21 January 2018

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Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults.

21 January 2018

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Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice.

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Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling

21 January 2018

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Echocardiographic abnormalities in normotensive obese patients: relationship with visceral fat.

21 January 2018

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Detection of superoxide in vascular tissue

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Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor

21 January 2018

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Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

21 January 2018

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Lipotoxicity and cardiac dysfunction in mammals andDrosophila

21 January 2018

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Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve

21 January 2018

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Leptin is essential in maintaining normal vascular compliance independent of body weight

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Role of circulatory congestion in the cardiorespiratory failure of obesity

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Retracted: Interaction between Age and Obesity on Cardiomyocyte Contractile Function: Role of Leptin and Stress Signaling

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Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species

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Prolonged oxidative stress inverts the cardiac force-frequency relation: role of altered calcium handling and myofilament calcium responsiveness

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Advanced glycation end-product cross-link breakers. A novel approach to cardiovascular pathologies related to the aging process

21 January 2018

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DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity

21 January 2018

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Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction.

21 January 2018

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Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention

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Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function

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12 December 2020

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

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12 December 2020

Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion

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12 December 2020

Do hypertension and aging have a similar effect on the myocardium?

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12 December 2020

Effect of leptin deficiency on metabolic rate in ob/ob mice

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12 December 2020

Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes

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12 December 2020

10.1007/S12265-013-9453-4

Identifiers

DOI

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Dimensions Publication ID

2 September 2017

1045643658

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