Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta (Q38302280)

1 September 2017

title

Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta (English)

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1 September 2017

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1 September 2017

Veena Vijayanathan

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1 September 2017

Norma J Greenfield

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1 September 2017

T J Thomas

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1 September 2017

Margarita M Ivanova

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1 September 2017

Valentyn V Tyulmenkov

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1 September 2017

Michael A Gallo

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1 September 2017

Thresia Thomas

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1 September 2017

publication date

1 February 2007

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Biochemistry and Cell Biology

1 September 2017

published in

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1 September 2017

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1 September 2017

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1 September 2017

page(s)

1-10

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Long-term exposure to tamoxifen induces hypersensitivity to estradiol

1 September 2017

cites work

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Interplay of flexibility and stability in the control of estrogen receptor activity.

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Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer

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The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex

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Increase in the stability and helical content of estrogen receptor alpha in the presence of the estrogen response element: analysis by circular dichroism spectroscopy

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Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements.

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Analysis of the molecular mechanisms of human estrogen receptors alpha and beta reveals differential specificity in target promoter regulation by xenoestrogens

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Visualization of single molecules of RNA polymerase sliding along DNA.

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Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.

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Therapeutic targeting in the estrogen receptor hormonal pathway

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A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor

21 January 2018

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Estrogen receptor interaction with estrogen response elements

21 January 2018

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Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors

21 January 2018

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Delineation of a unique protein-protein interaction site on the surface of the estrogen receptor

21 January 2018

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Cloning of a novel receptor expressed in rat prostate and ovary

21 January 2018

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Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

21 January 2018

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Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression

21 January 2018

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Understanding the selectivity of genistein for human estrogen receptor-beta using X-ray crystallography and computational methods

21 January 2018

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Estrogen signaling: a subtle balance between ER alpha and ER beta

21 January 2018

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Ligands differentially modulate the protein interactions of the human estrogen receptors alpha and beta

21 January 2018

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The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB.

21 January 2018

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A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains

21 January 2018

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Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer

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Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors

21 January 2018

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Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

21 January 2018

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Hydroxylapatite “batch” assay for estrogen receptors: Increased sensitivity over present receptor assays

21 January 2018

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Estrogen response element binding induces alterations in estrogen receptor-alpha conformation as revealed by susceptibility to partial proteolysis

21 January 2018

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Estrogen receptor beta isoforms exhibit differences in ligand-activated transcriptional activity in an estrogen response element sequence-dependent manner

21 January 2018

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Differential modulation of DNA conformation by estrogen receptors alpha and beta

21 January 2018

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Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells

21 January 2018

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Molecular determinants for the tissue specificity of SERMs

21 January 2018

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Structural alignment of protein--DNA interfaces: insights into the determinants of binding specificity.

21 January 2018

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Coregulator function: a key to understanding tissue specificity of selective receptor modulators

21 January 2018

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Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

21 January 2018

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Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases

21 January 2018

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Estrogen receptors alpha and beta exhibit different estradiol and estrogen response element binding in the presence of nonspecific DNA.

21 January 2018

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A mathematical approach to predict the affinity of estrogen receptors alpha and beta binding to DNA.

21 January 2018

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Allosteric modulation of estrogen receptor conformation by different estrogen response elements

21 January 2018

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The effects of estrogen-responsive element- and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ER alpha and ER beta

21 January 2018

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Smoothing and Differentiation of Data by Simplified Least Squares Procedures

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O06-144

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1 September 2017

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