The nucleolar localization domain of the catalytic subunit of human telomerase (Q38290133)

1 September 2017

title

The nucleolar localization domain of the catalytic subunit of human telomerase (English)

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1 September 2017

author name string

Katherine T Etheridge

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1 September 2017

Soma S R Banik

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1 September 2017

Blaine N Armbruster

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1 September 2017

Yusheng Zhu

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1 September 2017

Rebecca M Terns

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1 September 2017

Michael P Terns

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1 September 2017

Christopher M Counter

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1 September 2017

language of work or name

English

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publication date

15 April 2002

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

277

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1 September 2017

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1 September 2017

page(s)

24764-24770

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Role of telomerase in cellular proliferation and cancer

1 September 2017

cites work

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Reverse transcriptase motifs in the catalytic subunit of telomerase

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Human telomerase contains evolutionarily conserved catalytic and structural subunits

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Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

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Identification and analyses of the Xenopus TERT gene that encodes the catalytic subunit of telomerase

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Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans

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Expression of telomerase reverse transcriptase and telomere elongation during sexual maturation in Paramecium caudatum

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Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants

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N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

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Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase

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Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit

21 January 2018

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A telomerase component is defective in the human disease dyskeratosis congenita

21 January 2018

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In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs

21 January 2018

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Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10

21 January 2018

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Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p

21 January 2018

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Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle

21 January 2018

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The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

21 January 2018

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21 January 2018

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21 January 2018

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Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding

21 January 2018

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Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity

21 January 2018

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Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions

21 January 2018

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The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

21 January 2018

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Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

21 January 2018

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Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells

21 January 2018

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Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae

21 January 2018

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Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201227200

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1 September 2017

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