Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism (Q38298216)

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scientific article published on October 2007

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English	Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism	scientific article published on October 2007

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

apoptotic process

0 references

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

author name string

G Lescoat

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

K Chantrel-Groussard

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

N Pasdeloup

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

H Nick

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

P Brissot

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

F Gaboriau

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

publication date

1 October 2007

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Europe PubMed Central

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1 September 2017

Cell Proliferation

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

40

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

755-767

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Effect of iron chelators on proliferation and iron uptake in hepatoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Induction of a SSAT isoform in response to hypoxia or iron deficiency and its protective effects on cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Oral iron chelators--development and application

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Effect of thioacetamide, growth hormone or partial hepatectomy on spermidine acetylase activity of rat liver cytosol

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Development of tridentate iron chelators: from desferrithiocin to ICL670.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Involvement of polyamines in apoptosis. Facts and controversies: effectors or protectors?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Biochemical Characteristics of Caspases-3, -6, -7, and -8

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

A perspective of polyamine metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00468.X

21 January 2018

Effect of dietary iron deficiency or excess on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring chelation therapy to achieve optimal outcome in the treatment of thalassaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of differentiated and dedifferentiated clones from a rat hepatoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low iron state is associated with reduced tumor promotion in a two-stage mouse skin carcinogenesis model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine dependence of normal cell-cycle progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atmospheric pressure chemical ionization-mass spectrometry method to improve the determination of dansylated polyamines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant Increases in the Steady States of Putrescine and Spermidine/SpermineN1-Acetyltransferase mRNA in HeLa Cells Accompanied by Growth Arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulating effect of excess iron feeding on spontaneous lung tumor promotion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiproliferative effect of deferiprone on the Hep G2 cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alpha-difluoromethylornithine on the cyclin A expression in Hep-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of non-transferrin-bound iron in the pathogenesis of iron overload and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine modulation of iron uptake in CHO cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2184.2007.00468.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495977&resulttype=core&format=json

14 May 2020

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