CCR4 and its ligands: from bench to bedside (Q38236403)

31 August 2017

title

CCR4 and its ligands: from bench to bedside (English)

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31 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25087232%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kouji Matsushima

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25087232%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

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2 August 2014

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31 August 2017

published in

International Immunology

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1 June 2020

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25087232%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25087232%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

11-20

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25087232%20AND%20SRC:MED&resulttype=core&format=json

Chemokines: a new classification system and their role in immunity

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Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

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The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

21 January 2018

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C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential.

21 January 2018

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Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes

21 January 2018

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CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.

21 January 2018

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Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells

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Human peripheral blood T regulatory cells (Tregs), functionally primed CCR4+ Tregs and unprimed CCR4- Tregs, regulate effector T cells using FasL.

21 January 2018

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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

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The frequency of type 2 CD8+ T cells is increased in peripheral blood from patients with psoriasis vulgaris.

21 January 2018

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Human memory CCR4+CD8+ T cell subset has the ability to produce multiple cytokines

21 January 2018

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Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.

21 January 2018

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Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity

21 January 2018

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iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients

21 January 2018

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A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.

21 January 2018

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CC chemokine receptor 4 expression on peripheral blood CD4+ T cells reflects disease activity of atopic dermatitis

21 January 2018

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CCR4 in human allergen-induced late responses in the skin and lung

21 January 2018

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Characterization of chemokine receptor expression and cytokine production in circulating CD4+ T cells from patients with atopic dermatitis: up-regulation of C-C chemokine receptor 4 in atopic dermatitis

21 January 2018

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Preferential expression of T(h)2-type chemokine and its receptor in atopic dermatitis

21 January 2018

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Nickel-specific CD4(+) and CD8(+) T cells display distinct migratory responses to chemokines produced during allergic contact dermatitis.

21 January 2018

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Accumulation of CCR4-expressing CD4+ T cells and high concentration of its ligands (TARC and MDC) in bronchoalveolar lavage fluid of patients with eosinophilic pneumonia

21 January 2018

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CC chemokine receptor 4 ligand production by bronchoalveolar lavage fluid cells in cigarette-smoke-associated acute eosinophilic pneumonia.

21 January 2018

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Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity

21 January 2018

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Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis

21 January 2018

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IFN-gamma-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis

21 January 2018

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Increased levels of a TH2-type CC chemokine thymus and activation-regulated chemokine (TARC) in serum and induced sputum of asthmatics.

21 January 2018

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Systemic chemokine and chemokine receptor responses are divergent in allergic versus non-allergic humans

21 January 2018

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Thymus and activation-regulated chemokine as a clinical biomarker in atopic dermatitis

21 January 2018

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A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations

21 January 2018

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Cutting Edge: Chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4 T cells under physiological conditions.

21 January 2018

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Demonstration of TARC and CCR4 mRNA expression and distribution using in situ RT-PCR in the lesional skin of atopic dermatitis

21 January 2018

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

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Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor

21 January 2018

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CCR4-dependent regulatory T cell function in inflammatory bowel disease

21 January 2018

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Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

21 January 2018

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Accumulation of CCR4⁺CTLA-4 FOXP3⁺CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells

21 January 2018

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Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation.

21 January 2018

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Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

21 January 2018

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Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease

21 January 2018

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Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells

21 January 2018

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Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells

21 January 2018

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Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo

21 January 2018

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Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

21 January 2018

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CXC chemokine receptor 3 and CC chemokine receptor 4 expression in T-cell and NK-cell lymphomas with special reference to clinicopathological significance for peripheral T-cell lymphoma, unspecified.

21 January 2018

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Linkage of expression of chemokine receptors (CXCR3 and CCR4) and cytotoxic molecules in peripheral T cell lymphoma, not otherwise specified and ALK-negative anaplastic large cell lymphoma.

21 January 2018

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Tax-inducible production of CC chemokine ligand 22 by human T cell leukemia virus type 1 (HTLV-1)-infected T cells promotes preferential transmission of HTLV-1 to CCR4-expressing CD4+ T cells

21 January 2018

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Human T-lymphotropic virus type 1-induced CC chemokine ligand 22 maintains a high frequency of functional FoxP3+ regulatory T cells.

21 January 2018

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c‐Maf suppresses human T‐cell leukemia virus type 1 Tax by competing for CREB‐binding protein

21 January 2018

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Recent progress in the development of antagonists to the chemokine receptors CCR3 and CCR4.

21 January 2018

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A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens

21 January 2018

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Chemokine receptor antagonists: Part 1.

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Defucosylated chimeric anti-CC chemokine receptor 4 IgG1 with enhanced antibody-dependent cellular cytotoxicity shows potent therapeutic activity to T-cell leukemia and lymphoma

21 January 2018

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Enhanced natural killer cell binding and activation by low-fucose IgG1 antibody results in potent antibody-dependent cellular cytotoxicity induction at lower antigen density

21 January 2018

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The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-Cell leukemia/lymphoma

21 January 2018

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Defucosylated anti CC chemokine receptor 4 monoclonal antibody combined with immunomodulatory cytokines: a novel immunotherapy for aggressive/refractory Mycosis fungoides and Sezary syndrome

21 January 2018

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Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model

21 January 2018

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Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo

21 January 2018

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Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells

21 January 2018

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Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult T-cell leukemia/lymphoma.

21 January 2018

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Multicenter phase II study of mogamulizumab (KW-0761), a defucosylated anti-cc chemokine receptor 4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma

21 January 2018

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CCR4 as a novel molecular target for immunotherapy of cancer

21 January 2018

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Stevens-Johnson Syndrome associated with mogamulizumab treatment of adult T-cell leukemia / lymphoma

21 January 2018

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