The regulatory potential of upstream open reading frames in eukaryotic gene expression (Q38226318)

31 August 2017

title

The regulatory potential of upstream open reading frames in eukaryotic gene expression (English)

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31 August 2017

Klaus Wethmar

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31 August 2017

publication date

3 July 2014

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Wiley interdisciplinary reviews. RNA

31 August 2017

published in

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31 August 2017

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31 August 2017

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31 August 2017

page(s)

765-778

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Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast.

31 August 2017

cites work

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Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

21 January 2018

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Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

21 January 2018

1 reference

uAUG and uORFs in human and rodent 5'untranslated mRNAs

21 January 2018

1 reference

Evolutionary conservation suggests a regulatory function of AUG triplets in 5'-UTRs of eukaryotic genes

21 January 2018

1 reference

uORFdb--a comprehensive literature database on eukaryotic uORF biology.

21 January 2018

1 reference

The scanning mechanism of eukaryotic translation initiation

21 January 2018

1 reference

Pushing the limits of the scanning mechanism for initiation of translation

21 January 2018

1 reference

The mechanism of eukaryotic translation initiation and principles of its regulation

21 January 2018

1 reference

Role of two upstream open reading frames in the translational control of oncogene mdm2.

21 January 2018

1 reference

The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties

21 January 2018

1 reference

Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation

21 January 2018

1 reference

Differential regulation of oestrogen receptor β isoforms by 5' untranslated regions in cancer

21 January 2018

1 reference

Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor alpha

21 January 2018

1 reference

Molecular cloning and characterization of the mouse peroxiredoxin V gene

21 January 2018

1 reference

Upstream open reading frames regulate translation of Mona/Gads adapter mRNA in the megakaryocytic lineage

21 January 2018

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Extensive transcript diversity and novel upstream open reading frame regulation in yeast

21 January 2018

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Frac-seq reveals isoform-specific recruitment to polyribosomes

21 January 2018

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Variable promoter usage and alternative splicing in five mouse connexin genes.

21 January 2018

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Patterns, mechanisms, and functions of translation regulation in mammalian spermatogenic cells

21 January 2018

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The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

21 January 2018

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Position is the critical determinant for function of iron-responsive elements as translational regulators

21 January 2018

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Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs

21 January 2018

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Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control

21 January 2018

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Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes

21 January 2018

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Hidden coding potential of eukaryotic genomes: nonAUG started ORFs

21 January 2018

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Translation reinitiation relies on the interaction between eIF3a/TIF32 and progressively folded cis-acting mRNA elements preceding short uORFs

21 January 2018

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

21 January 2018

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At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

21 January 2018

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Analysis of oligonucleotide AUG start codon context in eukariotic mRNAs.

21 January 2018

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Constraints on reinitiation of translation in mammals

21 January 2018

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Reinitiation and recycling are distinct processes occurring downstream of translation termination in yeast.

21 January 2018

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Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes

21 January 2018

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Inhibition of CCAAT/enhancer-binding protein alpha and beta translation by upstream open reading frames

21 January 2018

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Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control

21 January 2018

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Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control

21 January 2018

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Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stability

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

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What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame?

21 January 2018

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Evidence for translational regulation of the activator of general amino acid control in yeast

21 January 2018

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Translational regulation of yeast GCN4. A window on factors that control initiator-trna binding to the ribosome

21 January 2018

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Translational regulation of GCN4 and the general amino acid control of yeast

21 January 2018

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Multiple upstream AUG codons mediate translational control of GCN4.

21 January 2018

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Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions

21 January 2018

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A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation

21 January 2018

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Translational regulation of the plant S-adenosylmethionine decarboxylase

21 January 2018

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uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs

21 January 2018

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Evolutionary changes in the fungal carbamoyl-phosphate synthetase small subunit gene and its associated upstream open reading frame

21 January 2018

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The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression

21 January 2018

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Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay

21 January 2018

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Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide

21 January 2018

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A conserved upstream open reading frame mediates sucrose-induced repression of translation

21 January 2018

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Inhibition of nascent-peptide release at translation termination

21 January 2018

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Regulation of RAR beta 2 mRNA expression: evidence for an inhibitory peptide encoded in the 5'-untranslated region

21 January 2018

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Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5'UTR

21 January 2018

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Trans-regulation of the expression of the transcription factor MtHAP2-1 by a uORF controls root nodule development.

21 January 2018

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Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

21 January 2018

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

21 January 2018

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High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans

21 January 2018

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Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast

21 January 2018

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Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions

21 January 2018

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

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Glutamine stimulates translation of uncoupling protein 2mRNA.

21 January 2018

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The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.

21 January 2018

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Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB

21 January 2018

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C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals

21 January 2018

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Translational control of SCL-isoform expression in hematopoietic lineage choice.

21 January 2018

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Negative and translation termination-dependent positive control of FLI-1 protein synthesis by conserved overlapping 5' upstream open reading frames in Fli-1 mRNA.

21 January 2018

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Ribosome shunt is essential for infectivity of cauliflower mosaic virus

21 January 2018

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Nonlinear ribosome migration on cauliflower mosaic virus 35S RNA

21 January 2018

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Termination and peptide release at the upstream open reading frame are required for downstream translation on synthetic shunt-competent mRNA leaders

21 January 2018

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Short ORF-dependent ribosome shunting operates in an RNA picorna-like virus and a DNA pararetrovirus that cause rice tungro disease

21 January 2018

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Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt

21 January 2018

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Translational control via protein-regulated upstream open reading frames.

21 January 2018

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Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

21 January 2018

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Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

21 January 2018

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Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress

21 January 2018

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The translational landscape of mTOR signalling steers cancer initiation and metastasis

21 January 2018

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A unifying model for mTORC1-mediated regulation of mRNA translation.

21 January 2018

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The translation of an antiapoptotic protein HIAP2 is regulated by an upstream open reading frame

21 January 2018

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An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA

21 January 2018

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Transgenic zebrafish model to study translational control mediated by upstream open reading frame of human chop gene

21 January 2018

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A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis

21 January 2018

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Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

21 January 2018

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Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs

21 January 2018

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Peptidomic discovery of short open reading frame-encoded peptides in human cells.

21 January 2018

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Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

21 January 2018

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sORF finder: a program package to identify small open reading frames with high coding potential

21 January 2018

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uPEPperoni: an online tool for upstream open reading frame location and analysis of transcript conservation

21 January 2018

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Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations

21 January 2018

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Gene expression regulation by upstream open reading frames and human disease

21 January 2018

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An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia

21 January 2018

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Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma

21 January 2018

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Identification of a U2HR gene mutation in Turkish families with Marie Unna hereditary hypotrichosis.

21 January 2018

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A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.

21 January 2018

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Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

21 January 2018

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Marie Unna hereditary hypotrichosis: Identification of a U2HR mutation in the family from the original 1925 report

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WRNA.1245

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31 August 2017

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