In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme (Q38200703)

30 August 2017

title

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme (English)

1 reference

30 August 2017

main subject

environmental protection

1 reference

1 reference

ToxCast

25 May 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Thomas Knudsen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Nisha Sipes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Matt Martin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

1 reference

22 April 2014

1 reference

Basic and Clinical Pharmacology and Toxicology

30 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

69-76

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

The ToxCast program for prioritizing toxicity testing of environmental chemicals

12 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

21 January 2018

1 reference

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Improving the human hazard characterization of chemicals: a Tox21 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

The exposure data landscape for manufactured chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Chemical genomics profiling of environmental chemical modulation of human nuclear receptors

21 January 2018

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https://api.crossref.org/works/10.1111%2FBCPT.12239

Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Using nuclear receptor activity to stratify hepatocarcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Endocrine profiling and prioritization of environmental chemicals using ToxCast data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Zebrafish developmental screening of the ToxCast™ Phase I chemical library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

A computational model predicting disruption of blood vessel development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Environmental impact on vascular development predicted by high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Predictive model of rat reproductive toxicity from ToxCast high throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

The toxicity data landscape for environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Disruption of embryonic vascular development in predictive toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

A comprehensive statistical analysis of predicting in vivo hazard using high-throughput in vitro screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Evaluation of the toxicity forecasting capability of EPA's ToxCast Phase I data: can ToxCast in vitro assays predict carcinogenicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

A framework for human relevance analysis of information on carcinogenic modes of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Overview: Using mode of action and life stage information to evaluate the human relevance of animal toxicity data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

IPCS framework for analyzing the relevance of a noncancer mode of action for humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Predictive models and computational toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Virtual tissues in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

Simulating microdosimetry in a virtual hepatic lobule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

ACToR — Aggregated Computational Toxicology Resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12239

21 January 2018

Identifiers

DOI

10.1111/BCPT.12239

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json

release_bwc6seljjvdpfmlq4oauqnfcyu

12 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bwc6seljjvdpfmlq4oauqnfcyu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24684691%20AND%20SRC:MED&resulttype=core&format=json